Characterization of a divergent non-classical MHC class I gene in sharks

Sharks are the most ancient group of vertebrates known to possess members of the major histocompatibility complex (MHC) gene family. For this reason, sharks provide a unique opportunity to gain insight into the evolution of the vertebrate immune system through comparative analysis. Two genes encodin...

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Veröffentlicht in:	Immunogenetics (New York) 2003-04, Vol.55 (1), p.57-61
Hauptverfasser:	Wang, Carren, Perera, Thushara V, Ford, Heide L, Dascher, Christopher C
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Antigen presentation Biological Evolution Cloning Cloning, Molecular Comparative analysis DNA Primers - chemistry DNA, Complementary - genetics Dogfish - genetics Evolution Gene Expression Genes Genes, MHC Class I - genetics Genetic Variation Humans Immune system Lymphocytes Mice Molecular Sequence Data Pathogens Peptides Phylogeny Proteins Reverse Transcriptase Polymerase Chain Reaction Sequence Analysis, DNA Sequence Homology, Amino Acid Sharks Spleen Vertebrates
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