TRALI due to granulocyte-agglutinating human neutrophil antigen-3a (5b) alloantibodies in donor plasma: a report of 2 fatalities

BACKGROUND : TRALI is usually an immunologic reaction to WBC antibodies in infused plasma and ranks second only to ABO mismatch as a cause of transfusion‐associated death. Implicated donors are usually multiparous women (≥3 pregnancies). STUDY DESIGN AND METHODS : Two fatal cases of TRALI were evalu...

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Veröffentlicht in:	Transfusion (Philadelphia, Pa.) Pa.), 2003-05, Vol.43 (5), p.641-645
Hauptverfasser:	Davoren, A., Curtis, B.R., Shulman, I.A., Mohrbacher, A.F., Bux, J., Kwiatkowska, B.J., McFarland, J.G., Aster, R.H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Agglutination Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Antibodies - immunology Biological and medical sciences Blood Donors Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis Fatal Outcome Female Granulocytes - physiology Humans Isoantigens - immunology Lung Diseases - etiology Lung Diseases - immunology Male Medical sciences Middle Aged Neutrophils - immunology Transfusion Reaction Transfusions. Complications. Transfusion reactions. Cell and gene therapy
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