Diminution of antibodies directed against tumor cell surface epitopes: A single chain Fv fusion molecule specifically recognizes the extracellular domain of the c- erbB-2 receptor

We are evaluating strategies for the inhibition of growth or the selective killing of tumor cells. Cell surface antigens which are exclusively expressed or which are enhanced in their expression in tumor cells might provide the means to target cytotoxic or cytostatic agents to these cells. Few tumor...

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Veröffentlicht in:The Journal of steroid biochemistry and molecular biology 1992-09, Vol.43 (1), p.1-7
Hauptverfasser: Wels, W., Harwerth, I.M., Hynes, N.E., Groner, B.
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Sprache:eng
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