Synthesis and X-ray crystal and solution structures of 2,5-anhydro-3,4- O-(1,2-ethanediyl)- d-mannitol: a locked 4T3 furanose conformer

2,5-Anhydro-3,4- O-(1,2-ethanedyl)- d-mannitol ( 1) was prepared from 2,5-anhydro- d-mannitol ( 2) in three steps. The fused ring system was introduced by a phase-transfer alkylation using 1,2-dibromoethane. Its conformation in solution was determined by NMR studies at 500 MHz. Variable-temperature...

Ausführliche Beschreibung