Effect of extrinsic denervation on muscarinic neurotransmission in the canine ileocolonic region

To explore the hypothesis that denervation hypersensitivity increases ileocolonic motor activity after extrinsic denervation, we compared muscarinic neurotransmission in canine ileocolonic loops that were isolated and either extrinsically innervated or extrinsically denervated. We recorded ileal, il...

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Veröffentlicht in:	Neurogastroenterology and motility 2003-04, Vol.15 (2), p.173-186
Hauptverfasser:	Leelakusolvong, S., Bharucha, A. E., Sarr, M. G., Hammond, P. I., Brimijoin, S., Phillips, S. F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals cholinergic Cholinesterases - analysis Cholinesterases - metabolism Colon - chemistry Colon - innervation Colon - physiology colonic motility Dogs extrinsic denervation Female Gastrointestinal Motility - drug effects Gastrointestinal Motility - physiology Ileum - chemistry Ileum - innervation Ileum - physiology Immunohistochemistry Muscarinic Antagonists - pharmacology Muscle Contraction - drug effects Muscle Contraction - physiology Muscle Denervation Muscle, Smooth - drug effects Muscle, Smooth - physiology Receptors, Muscarinic - physiology
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