Hantavirus infection with acute kidney failure
Hantavirus infection was confirmed by history, symptoms and biochemical changes, as well as immunofluorescence test in 29 patients (24 men, 5 women; mean age 36.9 +/- 11.5 years) with nontraumatic renal failure (ANF), retrospectively in 15 patients. Cardinal symptoms were acute onset (n = 29), fever...
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| Veröffentlicht in: | Deutsche medizinische Wochenschrift 1992-09, Vol.117 (38), p.1429-1433 |
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| container_title | Deutsche medizinische Wochenschrift |
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| creator | Kulzer, P Schaefer, R M Heidbreder, E Heidland, A |
| description | Hantavirus infection was confirmed by history, symptoms and biochemical changes, as well as immunofluorescence test in 29 patients (24 men, 5 women; mean age 36.9 +/- 11.5 years) with nontraumatic renal failure (ANF), retrospectively in 15 patients. Cardinal symptoms were acute onset (n = 29), fever (n = 27), pain in the flanks, abdomen or head (n = 27), reduced glomerular filtration rate (n = 29), proteinuria (n = 25) and thrombocytopenia (n = 16). Normal renal function was restored in all patients. Follow-up examination of 15 patients 6-7 years after the acute illness revealed normal blood pressure, normal serum creatinine, absent proteinuria and normal inulin clearance in all, thus confirming the favourable prognosis of the infection in Western Europe. Nonetheless, because Hantavirus infection is by no means rare, it should be included in the differential diagnosis of acute renal failure. |
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Cardinal symptoms were acute onset (n = 29), fever (n = 27), pain in the flanks, abdomen or head (n = 27), reduced glomerular filtration rate (n = 29), proteinuria (n = 25) and thrombocytopenia (n = 16). Normal renal function was restored in all patients. Follow-up examination of 15 patients 6-7 years after the acute illness revealed normal blood pressure, normal serum creatinine, absent proteinuria and normal inulin clearance in all, thus confirming the favourable prognosis of the infection in Western Europe. Nonetheless, because Hantavirus infection is by no means rare, it should be included in the differential diagnosis of acute renal failure.</description><identifier>ISSN: 0012-0472</identifier><identifier>PMID: 1356086</identifier><language>ger</language><publisher>Germany</publisher><subject>Acute Kidney Injury - diagnosis ; Acute Kidney Injury - epidemiology ; Acute Kidney Injury - etiology ; Adolescent ; Adult ; Antibodies, Viral - blood ; Biopsy ; Diagnosis, Differential ; Female ; Follow-Up Studies ; Hantavirus - immunology ; Hemorrhagic Fever with Renal Syndrome - complications ; Hemorrhagic Fever with Renal Syndrome - diagnosis ; Hemorrhagic Fever with Renal Syndrome - epidemiology ; Humans ; Kidney - pathology ; Male ; Middle Aged ; Prospective Studies ; Retrospective Studies</subject><ispartof>Deutsche medizinische Wochenschrift, 1992-09, Vol.117 (38), p.1429-1433</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1356086$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kulzer, P</creatorcontrib><creatorcontrib>Schaefer, R M</creatorcontrib><creatorcontrib>Heidbreder, E</creatorcontrib><creatorcontrib>Heidland, A</creatorcontrib><title>Hantavirus infection with acute kidney failure</title><title>Deutsche medizinische Wochenschrift</title><addtitle>Dtsch Med Wochenschr</addtitle><description>Hantavirus infection was confirmed by history, symptoms and biochemical changes, as well as immunofluorescence test in 29 patients (24 men, 5 women; mean age 36.9 +/- 11.5 years) with nontraumatic renal failure (ANF), retrospectively in 15 patients. Cardinal symptoms were acute onset (n = 29), fever (n = 27), pain in the flanks, abdomen or head (n = 27), reduced glomerular filtration rate (n = 29), proteinuria (n = 25) and thrombocytopenia (n = 16). Normal renal function was restored in all patients. Follow-up examination of 15 patients 6-7 years after the acute illness revealed normal blood pressure, normal serum creatinine, absent proteinuria and normal inulin clearance in all, thus confirming the favourable prognosis of the infection in Western Europe. Nonetheless, because Hantavirus infection is by no means rare, it should be included in the differential diagnosis of acute renal failure.</description><subject>Acute Kidney Injury - diagnosis</subject><subject>Acute Kidney Injury - epidemiology</subject><subject>Acute Kidney Injury - etiology</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Antibodies, Viral - blood</subject><subject>Biopsy</subject><subject>Diagnosis, Differential</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Hantavirus - immunology</subject><subject>Hemorrhagic Fever with Renal Syndrome - complications</subject><subject>Hemorrhagic Fever with Renal Syndrome - diagnosis</subject><subject>Hemorrhagic Fever with Renal Syndrome - epidemiology</subject><subject>Humans</subject><subject>Kidney - pathology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Prospective Studies</subject><subject>Retrospective Studies</subject><issn>0012-0472</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNotj0tLw0AURmeh1Fr7E4Ss3EVm5iY3k6UUtYWCm-7DPO7Q0bzMZJT-exWzOnxw-OBcsTXnQua8qOQNu43x_W_WUKzYSkCJXOGaPe51P-uvMKWYhd6TncPQZ99hPmfappmyj-B6umRehzZNdMeuvW4jbRdu2Onl-bTb58e318Pu6ZiPJWCO5GovrTOVFCSQqtobqgutJCr0gF4TOVF65Qic8RKNg0oCOqU95xZhwx7-b8dp-EwU56YL0VLb6p6GFJsKhFIc-K94v4jJdOSacQqdni7N0gc_1gNLbQ</recordid><startdate>19920918</startdate><enddate>19920918</enddate><creator>Kulzer, P</creator><creator>Schaefer, R M</creator><creator>Heidbreder, E</creator><creator>Heidland, A</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>19920918</creationdate><title>Hantavirus infection with acute kidney failure</title><author>Kulzer, P ; Schaefer, R M ; Heidbreder, E ; Heidland, A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p536-6ed9f2cdb721e16e79fbe94a82686f36faeed15f8de3dbf26bd37236d8af00c63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>ger</language><creationdate>1992</creationdate><topic>Acute Kidney Injury - diagnosis</topic><topic>Acute Kidney Injury - epidemiology</topic><topic>Acute Kidney Injury - etiology</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Antibodies, Viral - blood</topic><topic>Biopsy</topic><topic>Diagnosis, Differential</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Hantavirus - immunology</topic><topic>Hemorrhagic Fever with Renal Syndrome - complications</topic><topic>Hemorrhagic Fever with Renal Syndrome - diagnosis</topic><topic>Hemorrhagic Fever with Renal Syndrome - epidemiology</topic><topic>Humans</topic><topic>Kidney - pathology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Prospective Studies</topic><topic>Retrospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kulzer, P</creatorcontrib><creatorcontrib>Schaefer, R M</creatorcontrib><creatorcontrib>Heidbreder, E</creatorcontrib><creatorcontrib>Heidland, A</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Deutsche medizinische Wochenschrift</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kulzer, P</au><au>Schaefer, R M</au><au>Heidbreder, E</au><au>Heidland, A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hantavirus infection with acute kidney failure</atitle><jtitle>Deutsche medizinische Wochenschrift</jtitle><addtitle>Dtsch Med Wochenschr</addtitle><date>1992-09-18</date><risdate>1992</risdate><volume>117</volume><issue>38</issue><spage>1429</spage><epage>1433</epage><pages>1429-1433</pages><issn>0012-0472</issn><abstract>Hantavirus infection was confirmed by history, symptoms and biochemical changes, as well as immunofluorescence test in 29 patients (24 men, 5 women; mean age 36.9 +/- 11.5 years) with nontraumatic renal failure (ANF), retrospectively in 15 patients. 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| ispartof | Deutsche medizinische Wochenschrift, 1992-09, Vol.117 (38), p.1429-1433 |
| issn | 0012-0472 |
| language | ger |
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| source | MEDLINE; Thieme Connect Journals |
| subjects | Acute Kidney Injury - diagnosis Acute Kidney Injury - epidemiology Acute Kidney Injury - etiology Adolescent Adult Antibodies, Viral - blood Biopsy Diagnosis, Differential Female Follow-Up Studies Hantavirus - immunology Hemorrhagic Fever with Renal Syndrome - complications Hemorrhagic Fever with Renal Syndrome - diagnosis Hemorrhagic Fever with Renal Syndrome - epidemiology Humans Kidney - pathology Male Middle Aged Prospective Studies Retrospective Studies |
| title | Hantavirus infection with acute kidney failure |
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