Mechanotransduction via the elastin–laminin receptor (ELR) in resistance arteries

The arterial wall is composed of dynamically interacting cellular and acellular components that are necessary for the maintenance of vessel homeostasis. Two extracellular proteins in the vessel wall, elastin and laminin, play important structural roles. We recently established a role for the elastin...

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Veröffentlicht in:	Journal of biomechanics 2003-05, Vol.36 (5), p.645-652
Hauptverfasser:	Spofford, Christina M., Chilian, William M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Pressure - physiology c-fos Cell culture Cerebral Arteries - cytology Cerebral Arteries - physiology Coronary vessels Culture Techniques Elastin - physiology Gene Expression Regulation - physiology Glyceraldehyde-3-Phosphate Dehydrogenases - genetics Glyceraldehyde-3-Phosphate Dehydrogenases - metabolism Hemostasis - physiology Isolated vessels Laboratory animals Laminin - physiology Male Mechanoreceptors - physiology Mechanotransduction, Cellular - physiology Medical research Mesenteric Arteries - cytology Mesenteric Arteries - physiology Muscle, Smooth, Vascular - cytology Muscle, Smooth, Vascular - physiology Muscular system Physical Stimulation - methods Pressure Proteins Proto-Oncogene Proteins c-fos - genetics Proto-Oncogene Proteins c-fos - metabolism Rats Rats, Wistar Receptors, Cell Surface - physiology RNA, Messenger - analysis RNA, Messenger - metabolism Rodents Smooth muscle Stress, Mechanical Stretch Vascular Resistance - physiology Vascular smooth muscle Veins & arteries
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