Increasing the dietary (n-3) to (n-6) polyunsaturated fatty acid ratio increases tumor necrosis factor production by murine resident peritoneal macrophages without an effect on elicited peritoneal macrophages

Tumor necrosis factor (TNF), prostaglandin (PG) E2 and 6-keto-PGF,1 alpha production by murine peritoneal macrophages was monitored following in vitro stimulation with lipopolysaccharide. Macrophages were obtained from mice fed diets containing increasing ratios of (n-3) to (n-6) fatty acids by addi...

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Veröffentlicht in:	The Journal of nutrition 1992-10, Vol.122 (10), p.1942-1951
Hauptverfasser:	Hardardottir, I. (Cornell University, Ithaca, NY), Kinsella, J.E
Format:	Artikel
Sprache:	eng
Schlagworte:	6-Ketoprostaglandin F1 alpha - analysis ACIDE GRAS INSATURE ACIDOS GRASOS INSATURADOS Animals Biological and medical sciences BIOSINTESIS BIOSYNTHESE Cell Count DIETA Dietary Fats, Unsaturated - administration & dosage Dinoprostone - analysis FAGOCITOS Fatty Acids - analysis Fatty Acids, Omega-3 - administration & dosage Fatty Acids, Omega-6 Fatty Acids, Unsaturated - administration & dosage Female Fundamental and applied biological sciences. Psychology Fundamental immunology Immunobiology Lipopolysaccharides Macrophages - drug effects Macrophages - metabolism Mice Mice, Inbred BALB C Modulation of the immune response (stimulation, suppression) NECROSE NECROSIS NEOPLASMAS NEOPLASME PEPTIDE PEPTIDOS PERITOINE PERITONEO Peritoneum PHAGOCYTE Phospholipids - analysis RATON REGIME ALIMENTAIRE SOURIS Tumor Necrosis Factor-alpha - biosynthesis
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