IFN increases class I MHC antigen expression on adenovirus-infected human cells without inducing resistance to natural killer cell killing

It has been previously shown that unstimulated NK cells cannot preferentially lyse adenovirus serotypes 2 and 5-infected human cells. In this study, the ability of IFN to promote the selective NK cell-mediated lysis of adenovirus-infected human cells was determined. The relationship between target c...

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Veröffentlicht in:	The Journal of immunology (1950) 1992-10, Vol.149 (7), p.2372-2377
1. Verfasser:	Routes, JM
Format:	Artikel
Sprache:	eng
Schlagworte:	adenovirus Adenovirus Infections, Human - immunology Adenoviruses, Human - physiology Biological and medical sciences Cell Line Cytotoxic reactions (adcc reaction, cell-mediated lympholysis, complement-dependent cytotoxicity and others) Cytotoxicity, Immunologic - drug effects Fundamental and applied biological sciences. Psychology Fundamental immunology Histocompatibility Antigens Class I - biosynthesis Humans Immunobiology Immunological reactions in vitro Interferons - pharmacology Killer Cells, Natural - immunology
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