Ultrastructural characterization of effector-target interactions for human neonatal and adult NK cells reveals reduced intercellular surface contacts of neonatal cells

Limitations in neonatal natural killer (NK) cell responses may be associated with the less efficient newborn capacity to solve viral infections. Although these limitations have been extensively reported they are poorly characterized. Making use of the major histocompatibility complex (MHC) class I n...

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Veröffentlicht in:Human immunology 2003-05, Vol.64 (5), p.490-496
Hauptverfasser: Ribeiro-do-Couto, Laura M, Poelen, Martien, Hooibrink, Berend, Dormans, Jan A.M.A, Roholl, Paul J.M, Boog, Claire J.P
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Sprache:eng
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