Role of class D L-type Ca2+ channels for cochlear morphology

Voltage-gated Ca(2+) channels formed by subunits (class D Ca(2+) channels) tightly regulate neurotransmitter release from cochlear inner hair cells (IHCs) by controlling the majority of depolarisation-induced Ca(2+) entry. We have recently shown that the absence of these channels can cause deafness...

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Veröffentlicht in:	Hearing research 2003-04, Vol.178 (1-2), p.95-105
Hauptverfasser:	GLUECKERT, R, WIETZORREK, G, KAMMEN-JOLLY, K, SCHOLTZ, A, STEPHAN, K, STRIESSNIG, J, SCHROTT-FISCHER, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - metabolism Animals Animals, Newborn - anatomy & histology Animals, Newborn - growth & development Animals, Newborn - metabolism Biological and medical sciences Calcium Channels, L-Type - physiology Cochlea - ultrastructure Ear, auditive nerve, cochleovestibular tract, facial nerve: diseases, semeiology Medical sciences Mice Mice, Inbred C57BL Mice, Knockout Microscopy, Electron Non tumoral diseases Otorhinolaryngology. Stomatology
Online-Zugang:	Volltext
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