Treatment of Bacterial Vaginosis with Lactobacilli
60 women with bacterial vaginosis were entered into a double blind, placebo-controlled treatment trial with lyophilized Lactobacillus acidophilus. The lactobacilli used were producing H₂O₂. Immediately after completion of treatment, 16 out of 28 women who were treated with lactobacilli had normal va...
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Veröffentlicht in: | Sexually transmitted diseases 1992-05, Vol.19 (3), p.146-148 |
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creator | HALLÉN, ANDERS JARSTRAND, CONNIE PÅHLSON, CALLE |
description | 60 women with bacterial vaginosis were entered into a double blind, placebo-controlled treatment trial with lyophilized Lactobacillus acidophilus. The lactobacilli used were producing H₂O₂. Immediately after completion of treatment, 16 out of 28 women who were treated with lactobacilli had normal vaginal wet smear results, in comparison to none of the 29 women treated with placebo. All women harboured Bacteroides at inclusion. Bacteroides was eliminated from the vagina of 12 out of 16 healthy women after treatment. Only three of the women who received the Lactobacillus suppository were free of bacterial vaginosis after the subsequent menstruation. |
doi_str_mv | 10.1097/00007435-199205000-00007 |
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The lactobacilli used were producing H₂O₂. Immediately after completion of treatment, 16 out of 28 women who were treated with lactobacilli had normal vaginal wet smear results, in comparison to none of the 29 women treated with placebo. All women harboured Bacteroides at inclusion. Bacteroides was eliminated from the vagina of 12 out of 16 healthy women after treatment. Only three of the women who received the Lactobacillus suppository were free of bacterial vaginosis after the subsequent menstruation.</description><identifier>ISSN: 0148-5717</identifier><identifier>EISSN: 1537-4521</identifier><identifier>DOI: 10.1097/00007435-199205000-00007</identifier><identifier>PMID: 1523530</identifier><identifier>CODEN: STRDDM</identifier><language>eng</language><publisher>Hagerstown, MD: J. B. Lippincott Company</publisher><subject>Adolescent ; Adult ; Biological and medical sciences ; Double-Blind Method ; Female ; Follow-Up Studies ; Humans ; Lactobacillus acidophilus ; Male ; Medical sciences ; Pharmacology. Drug treatments ; Suppositories ; Vagina - microbiology ; Vaginal Smears ; Vaginosis, Bacterial - diagnosis ; Vaginosis, Bacterial - therapy</subject><ispartof>Sexually transmitted diseases, 1992-05, Vol.19 (3), p.146-148</ispartof><rights>Copyright 1992 American Venereal Disease Association</rights><rights>1993 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c481t-c1d079a8b6b010652dc2eba2b9a849b6a4400123b8017bc9c821f0ce3358c7c3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/44964432$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/44964432$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>309,310,314,776,780,785,786,799,23911,23912,25120,27903,27904,57995,58228</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4347365$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1523530$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>HALLÉN, ANDERS</creatorcontrib><creatorcontrib>JARSTRAND, CONNIE</creatorcontrib><creatorcontrib>PÅHLSON, CALLE</creatorcontrib><title>Treatment of Bacterial Vaginosis with Lactobacilli</title><title>Sexually transmitted diseases</title><addtitle>Sex Transm Dis</addtitle><description>60 women with bacterial vaginosis were entered into a double blind, placebo-controlled treatment trial with lyophilized Lactobacillus acidophilus. The lactobacilli used were producing H₂O₂. Immediately after completion of treatment, 16 out of 28 women who were treated with lactobacilli had normal vaginal wet smear results, in comparison to none of the 29 women treated with placebo. All women harboured Bacteroides at inclusion. Bacteroides was eliminated from the vagina of 12 out of 16 healthy women after treatment. Only three of the women who received the Lactobacillus suppository were free of bacterial vaginosis after the subsequent menstruation.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Double-Blind Method</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Lactobacillus acidophilus</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Pharmacology. Drug treatments</subject><subject>Suppositories</subject><subject>Vagina - microbiology</subject><subject>Vaginal Smears</subject><subject>Vaginosis, Bacterial - diagnosis</subject><subject>Vaginosis, Bacterial - therapy</subject><issn>0148-5717</issn><issn>1537-4521</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFUMtOwzAQtBColMInIOWAuAW8fsTxERAvqRKXiqtluw64SuJip0L8PS4p7V5WOzM7uxqECsA3gKW4xbkEo7wEKQnmeSr_oCM0BU5FyTiBYzTFwOqSCxCn6CylFd7OGCZoApxQTvEUkUV0euhcPxShKe61HVz0ui3e9YfvQ_Kp-PbDZzHPRDDa-rb15-ik0W1yF7s-Q4unx8XDSzl_e359uJuXltUwlBaWWEhdm8pgwBUnS0uc0cRkjElTacbyP4Sa_JEwVtqaQIOto5TXVlg6Q9ej7TqGr41Lg-p8sq5tde_CJilBQVDJZRbWo9DGkFJ0jVpH3-n4owCrbVrqPy21T2uE8url7sbGdG55WBzjyfzVjtfJ6raJurc-7WWMMkErfrBZpSHEA81kxRgl9BeGxHm9</recordid><startdate>19920501</startdate><enddate>19920501</enddate><creator>HALLÉN, ANDERS</creator><creator>JARSTRAND, CONNIE</creator><creator>PÅHLSON, CALLE</creator><general>J. 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Drug treatments</topic><topic>Suppositories</topic><topic>Vagina - microbiology</topic><topic>Vaginal Smears</topic><topic>Vaginosis, Bacterial - diagnosis</topic><topic>Vaginosis, Bacterial - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>HALLÉN, ANDERS</creatorcontrib><creatorcontrib>JARSTRAND, CONNIE</creatorcontrib><creatorcontrib>PÅHLSON, CALLE</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Sexually transmitted diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>HALLÉN, ANDERS</au><au>JARSTRAND, CONNIE</au><au>PÅHLSON, CALLE</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Treatment of Bacterial Vaginosis with Lactobacilli</atitle><jtitle>Sexually transmitted diseases</jtitle><addtitle>Sex Transm Dis</addtitle><date>1992-05-01</date><risdate>1992</risdate><volume>19</volume><issue>3</issue><spage>146</spage><epage>148</epage><pages>146-148</pages><issn>0148-5717</issn><eissn>1537-4521</eissn><coden>STRDDM</coden><abstract>60 women with bacterial vaginosis were entered into a double blind, placebo-controlled treatment trial with lyophilized Lactobacillus acidophilus. The lactobacilli used were producing H₂O₂. Immediately after completion of treatment, 16 out of 28 women who were treated with lactobacilli had normal vaginal wet smear results, in comparison to none of the 29 women treated with placebo. All women harboured Bacteroides at inclusion. Bacteroides was eliminated from the vagina of 12 out of 16 healthy women after treatment. Only three of the women who received the Lactobacillus suppository were free of bacterial vaginosis after the subsequent menstruation.</abstract><cop>Hagerstown, MD</cop><pub>J. B. Lippincott Company</pub><pmid>1523530</pmid><doi>10.1097/00007435-199205000-00007</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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ispartof | Sexually transmitted diseases, 1992-05, Vol.19 (3), p.146-148 |
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language | eng |
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source | Jstor Complete Legacy; MEDLINE; Journals@Ovid Complete |
subjects | Adolescent Adult Biological and medical sciences Double-Blind Method Female Follow-Up Studies Humans Lactobacillus acidophilus Male Medical sciences Pharmacology. Drug treatments Suppositories Vagina - microbiology Vaginal Smears Vaginosis, Bacterial - diagnosis Vaginosis, Bacterial - therapy |
title | Treatment of Bacterial Vaginosis with Lactobacilli |
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