Exploring the regulation of the expression of ChAT and VAChT genes in NG108-15 cells: Implication of PKA and PI3K signaling pathways

Involvement of different protein kinases regulated by cAMP and implication of muscarinic receptors in the regulation of choline acetyltransferase (ChAT) and vesicular acetylcholine transporter (VAChT) mRNA levels and ChAT activity has been studied in NG108-15 cells. Dibutyryl cAMP enhanced both ChAT...

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Veröffentlicht in:	Neurochem Res 2003-04, Vol.28 (3-4), p.557-564
Hauptverfasser:	CASTELL, Xavier, CHEVIRON, Nathalie, BARNIER, Jean-Vianney, DIEBLER, Marie-Francoise
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-Kinase Animals Biological and medical sciences Bucladesine Bucladesine - pharmacology Carrier Proteins Carrier Proteins - genetics Choline O-Acetyltransferase Choline O-Acetyltransferase - genetics Choline O-Acetyltransferase - metabolism Chromones Chromones - pharmacology Cyclic AMP Cyclic AMP - physiology Cyclic AMP-Dependent Protein Kinases Cyclic AMP-Dependent Protein Kinases - metabolism Enzyme Inhibitors Enzyme Inhibitors - pharmacology Fundamental and applied biological sciences. Psychology Gene Expression Regulation Hybridomas Isoquinolines Isoquinolines - pharmacology Life Sciences Membrane Transport Proteins Mice Morpholines Morpholines - pharmacology Neurons and Cognition Phosphatidylinositol 3-Kinases - metabolism Rats Receptors, Muscarinic Receptors, Muscarinic - physiology RNA, Messenger RNA, Messenger - antagonists & inhibitors RNA, Messenger - metabolism Signal Transduction Signal Transduction - physiology Sulfonamides Tumor Cells, Cultured Vesicular Acetylcholine Transport Proteins Vesicular Transport Proteins
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