Sheehan Syndrome: A Splinter of the Mind
A 40-year-old woman presented with headache and diplopia after hypotension from postpartum hemorrhage. A noncontrasted cranial magnetic resonance imaging (MRI) showed an enlarged pituitary with a rim of slight increased signal. A repeat gadolinium-enhanced cranial MRI showed peripheral enhancement o...
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Veröffentlicht in: | Survey of ophthalmology 2003-03, Vol.48 (2), p.230-233 |
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description | A 40-year-old woman presented with headache and diplopia after hypotension from postpartum hemorrhage. A noncontrasted cranial magnetic resonance imaging (MRI) showed an enlarged pituitary with a rim of slight increased signal. A repeat gadolinium-enhanced cranial MRI showed peripheral enhancement of the pituitary gland surrounding an isointense central area consistent with infarction of the pituitary and the clinical diagnosis of Sheehan syndrome. The patient was treated with intravenous hydrocortisone. Immediately after treatment, her symptoms remitted and the examination normalized. One month later, a gadolinium-enhanced cranial MRI was normal. The characteristic appearance of the post-gadolinium enhanced cranial MRI helped confirm the diagnosis of Sheehan syndrome and facilitate early treatment with corticosteroids. |
doi_str_mv | 10.1016/S0039-6257(02)00459-9 |
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A noncontrasted cranial magnetic resonance imaging (MRI) showed an enlarged pituitary with a rim of slight increased signal. A repeat gadolinium-enhanced cranial MRI showed peripheral enhancement of the pituitary gland surrounding an isointense central area consistent with infarction of the pituitary and the clinical diagnosis of Sheehan syndrome. The patient was treated with intravenous hydrocortisone. Immediately after treatment, her symptoms remitted and the examination normalized. One month later, a gadolinium-enhanced cranial MRI was normal. The characteristic appearance of the post-gadolinium enhanced cranial MRI helped confirm the diagnosis of Sheehan syndrome and facilitate early treatment with corticosteroids.</description><identifier>ISSN: 0039-6257</identifier><identifier>EISSN: 1879-3304</identifier><identifier>DOI: 10.1016/S0039-6257(02)00459-9</identifier><identifier>PMID: 12686307</identifier><identifier>CODEN: SUOPAD</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Biological and medical sciences ; cranial MRI ; Delivery. Postpartum. Lactation ; Disorders ; Female ; Glucocorticoids - therapeutic use ; Gynecology. Andrology. Obstetrics ; Humans ; Hydrocortisone - therapeutic use ; Hypopituitarism - diagnosis ; Hypopituitarism - drug therapy ; Hypopituitarism - etiology ; Hypotension - complications ; Hypotension - diagnosis ; Hypotension - drug therapy ; Infusions, Intravenous ; Magnetic Resonance Imaging ; Medical sciences ; Necrosis ; pituitary apoplexy ; Pituitary Gland, Anterior - pathology ; postpartum hemorrhage ; Postpartum Hemorrhage - complications ; Postpartum Hemorrhage - drug therapy ; Pregnancy ; Sheehan syndrome ; Treatment Outcome</subject><ispartof>Survey of ophthalmology, 2003-03, Vol.48 (2), p.230-233</ispartof><rights>2003 Elsevier Science Inc.</rights><rights>2003 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c345t-3765ac1a7be979af4d2975380a12831825695b6f17c7d043e45dbfb33ae7a3e43</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0039-6257(02)00459-9$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14707834$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12686307$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vaphiades, Michael S</creatorcontrib><creatorcontrib>Simmons, Debra</creatorcontrib><creatorcontrib>Archer, Robert L</creatorcontrib><creatorcontrib>Stringer, Warren</creatorcontrib><title>Sheehan Syndrome: A Splinter of the Mind</title><title>Survey of ophthalmology</title><addtitle>Surv Ophthalmol</addtitle><description>A 40-year-old woman presented with headache and diplopia after hypotension from postpartum hemorrhage. A noncontrasted cranial magnetic resonance imaging (MRI) showed an enlarged pituitary with a rim of slight increased signal. A repeat gadolinium-enhanced cranial MRI showed peripheral enhancement of the pituitary gland surrounding an isointense central area consistent with infarction of the pituitary and the clinical diagnosis of Sheehan syndrome. The patient was treated with intravenous hydrocortisone. Immediately after treatment, her symptoms remitted and the examination normalized. One month later, a gadolinium-enhanced cranial MRI was normal. The characteristic appearance of the post-gadolinium enhanced cranial MRI helped confirm the diagnosis of Sheehan syndrome and facilitate early treatment with corticosteroids.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>cranial MRI</subject><subject>Delivery. Postpartum. Lactation</subject><subject>Disorders</subject><subject>Female</subject><subject>Glucocorticoids - therapeutic use</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Hydrocortisone - therapeutic use</subject><subject>Hypopituitarism - diagnosis</subject><subject>Hypopituitarism - drug therapy</subject><subject>Hypopituitarism - etiology</subject><subject>Hypotension - complications</subject><subject>Hypotension - diagnosis</subject><subject>Hypotension - drug therapy</subject><subject>Infusions, Intravenous</subject><subject>Magnetic Resonance Imaging</subject><subject>Medical sciences</subject><subject>Necrosis</subject><subject>pituitary apoplexy</subject><subject>Pituitary Gland, Anterior - pathology</subject><subject>postpartum hemorrhage</subject><subject>Postpartum Hemorrhage - complications</subject><subject>Postpartum Hemorrhage - drug therapy</subject><subject>Pregnancy</subject><subject>Sheehan syndrome</subject><subject>Treatment Outcome</subject><issn>0039-6257</issn><issn>1879-3304</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0FtLwzAUB_AgipvTj6D0RZkP1ZOmaRpfZAxvMPGh-hzS5JRFunYmnbBvb3dRnw4HfpzLn5BzCjcUaHZbADAZZwkXY0iuAVIuY3lAhjQXMmYM0kMy_CMDchLCJ_SKSXFMBjTJ8oyBGJJxMUec6yYq1o317QLvoklULGvXdOijtoq6OUavrrGn5KjSdcCzfR2Rj8eH9-lzPHt7eplOZrFhKe9iJjKuDdWiRCmkrlKbSMFZDpomOaN5wjPJy6yiwgjbn4Mpt2VVMqZR6L5jI3K1m7v07dcKQ6cWLhisa91guwpKMCqAg-jhxR6uygVatfRuof1a_f7Wg8s90MHouvK6MS78u1SAyNlm4_3OYf_Wt0OvgnHYGLTOo-mUbZ2ioDapq23qahOpgkRtU1eS_QAdX2-6</recordid><startdate>20030301</startdate><enddate>20030301</enddate><creator>Vaphiades, Michael S</creator><creator>Simmons, Debra</creator><creator>Archer, Robert L</creator><creator>Stringer, Warren</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20030301</creationdate><title>Sheehan Syndrome: A Splinter of the Mind</title><author>Vaphiades, Michael S ; Simmons, Debra ; Archer, Robert L ; Stringer, Warren</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c345t-3765ac1a7be979af4d2975380a12831825695b6f17c7d043e45dbfb33ae7a3e43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>cranial MRI</topic><topic>Delivery. Postpartum. Lactation</topic><topic>Disorders</topic><topic>Female</topic><topic>Glucocorticoids - therapeutic use</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Hydrocortisone - therapeutic use</topic><topic>Hypopituitarism - diagnosis</topic><topic>Hypopituitarism - drug therapy</topic><topic>Hypopituitarism - etiology</topic><topic>Hypotension - complications</topic><topic>Hypotension - diagnosis</topic><topic>Hypotension - drug therapy</topic><topic>Infusions, Intravenous</topic><topic>Magnetic Resonance Imaging</topic><topic>Medical sciences</topic><topic>Necrosis</topic><topic>pituitary apoplexy</topic><topic>Pituitary Gland, Anterior - pathology</topic><topic>postpartum hemorrhage</topic><topic>Postpartum Hemorrhage - complications</topic><topic>Postpartum Hemorrhage - drug therapy</topic><topic>Pregnancy</topic><topic>Sheehan syndrome</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vaphiades, Michael S</creatorcontrib><creatorcontrib>Simmons, Debra</creatorcontrib><creatorcontrib>Archer, Robert L</creatorcontrib><creatorcontrib>Stringer, Warren</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Survey of ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vaphiades, Michael S</au><au>Simmons, Debra</au><au>Archer, Robert L</au><au>Stringer, Warren</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sheehan Syndrome: A Splinter of the Mind</atitle><jtitle>Survey of ophthalmology</jtitle><addtitle>Surv Ophthalmol</addtitle><date>2003-03-01</date><risdate>2003</risdate><volume>48</volume><issue>2</issue><spage>230</spage><epage>233</epage><pages>230-233</pages><issn>0039-6257</issn><eissn>1879-3304</eissn><coden>SUOPAD</coden><abstract>A 40-year-old woman presented with headache and diplopia after hypotension from postpartum hemorrhage. A noncontrasted cranial magnetic resonance imaging (MRI) showed an enlarged pituitary with a rim of slight increased signal. A repeat gadolinium-enhanced cranial MRI showed peripheral enhancement of the pituitary gland surrounding an isointense central area consistent with infarction of the pituitary and the clinical diagnosis of Sheehan syndrome. The patient was treated with intravenous hydrocortisone. Immediately after treatment, her symptoms remitted and the examination normalized. One month later, a gadolinium-enhanced cranial MRI was normal. The characteristic appearance of the post-gadolinium enhanced cranial MRI helped confirm the diagnosis of Sheehan syndrome and facilitate early treatment with corticosteroids.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>12686307</pmid><doi>10.1016/S0039-6257(02)00459-9</doi><tpages>4</tpages></addata></record> |
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subjects | Adult Biological and medical sciences cranial MRI Delivery. Postpartum. Lactation Disorders Female Glucocorticoids - therapeutic use Gynecology. Andrology. Obstetrics Humans Hydrocortisone - therapeutic use Hypopituitarism - diagnosis Hypopituitarism - drug therapy Hypopituitarism - etiology Hypotension - complications Hypotension - diagnosis Hypotension - drug therapy Infusions, Intravenous Magnetic Resonance Imaging Medical sciences Necrosis pituitary apoplexy Pituitary Gland, Anterior - pathology postpartum hemorrhage Postpartum Hemorrhage - complications Postpartum Hemorrhage - drug therapy Pregnancy Sheehan syndrome Treatment Outcome |
title | Sheehan Syndrome: A Splinter of the Mind |
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