Bone Mass, Size, and Density in Children and Adolescents With Osteogenesis Imperfecta: Effect of Intravenous Pamidronate Therapy

Cyclical intravenous therapy with pamidronate improves the clinical course in children and adolescents with osteogenesis imperfecta (OI). In this study, we evaluated the effect of this therapy on lumbar spine bone mass (bone mineral content [BMC]), size (bone volume [BV]), and density (volumetric bo...

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Veröffentlicht in:	Journal of bone and mineral research 2003-04, Vol.18 (4), p.610-614
Hauptverfasser:	Rauch, Frank, Plotkin, Horacio, Zeitlin, Leonid, Glorieux, Francis H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Biological and medical sciences bisphosphonate Bone and Bones - drug effects Bone and Bones - pathology Bone Density - drug effects bone fragility Bones, joints and connective tissue. Antiinflammatory agents Child Child, Preschool Diphosphonates - administration & dosage Female Humans Infant Infusions, Intravenous Lumbar Vertebrae - drug effects Lumbar Vertebrae - metabolism Lumbar Vertebrae - pathology Male Medical sciences Osteogenesis Imperfecta - drug therapy Osteogenesis Imperfecta - metabolism Osteogenesis Imperfecta - pathology osteoporosis pediatric Pharmacology. Drug treatments
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