Cardiac valve replacement in patients infected with the human immunodeficiency virus
Major surgical procedures, especially when performed under general anesthesia, can depress immunological parameters measured in vitro. Therefore concern has been expressed that operation might have an adverse effect on the immune status of individuals infected with the human immunodeficiency virus (...
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Veröffentlicht in: | The Annals of thoracic surgery 1992-09, Vol.54 (3), p.552-554 |
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container_title | The Annals of thoracic surgery |
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creator | Bräu, Norbert Esposito, Rick A. Simberkoff, Michael S. |
description | Major surgical procedures, especially when performed under general anesthesia, can depress immunological parameters measured in vitro. Therefore concern has been expressed that operation might have an adverse effect on the immune status of individuals infected with the human immunodeficiency virus (HIV). Four HIV-positive patients without symptoms of HIV disease underwent cardiac valve replacement in consequence of infective endocarditis. After up to 15 months postoperalively, 3 patients are alive and well without signs of progressive immunodeficiency or recurrent endocarditis. One patient died of recurrent endocarditis without evidence of HIV-related disease on autopsy. Cardiac operation does not seem to accelerate HIV-related immunodeficiency. |
doi_str_mv | 10.1016/0003-4975(92)90453-B |
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Therefore concern has been expressed that operation might have an adverse effect on the immune status of individuals infected with the human immunodeficiency virus (HIV). Four HIV-positive patients without symptoms of HIV disease underwent cardiac valve replacement in consequence of infective endocarditis. After up to 15 months postoperalively, 3 patients are alive and well without signs of progressive immunodeficiency or recurrent endocarditis. One patient died of recurrent endocarditis without evidence of HIV-related disease on autopsy. Cardiac operation does not seem to accelerate HIV-related immunodeficiency.</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/0003-4975(92)90453-B</identifier><identifier>PMID: 1510525</identifier><identifier>CODEN: ATHSAK</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; AIDS/HIV ; Biological and medical sciences ; Bioprosthesis ; Endocarditis, Bacterial - complications ; Endocarditis, Bacterial - surgery ; Heart Valve Diseases - complications ; Heart Valve Diseases - surgery ; Heart Valve Prosthesis ; HIV Infections - complications ; Humans ; Male ; Medical sciences ; Surgery (general aspects). Transplantations, organ and tissue grafts. 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Therefore concern has been expressed that operation might have an adverse effect on the immune status of individuals infected with the human immunodeficiency virus (HIV). Four HIV-positive patients without symptoms of HIV disease underwent cardiac valve replacement in consequence of infective endocarditis. After up to 15 months postoperalively, 3 patients are alive and well without signs of progressive immunodeficiency or recurrent endocarditis. One patient died of recurrent endocarditis without evidence of HIV-related disease on autopsy. Cardiac operation does not seem to accelerate HIV-related immunodeficiency.</description><subject>Adult</subject><subject>AIDS/HIV</subject><subject>Biological and medical sciences</subject><subject>Bioprosthesis</subject><subject>Endocarditis, Bacterial - complications</subject><subject>Endocarditis, Bacterial - surgery</subject><subject>Heart Valve Diseases - complications</subject><subject>Heart Valve Diseases - surgery</subject><subject>Heart Valve Prosthesis</subject><subject>HIV Infections - complications</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the heart</subject><issn>0003-4975</issn><issn>1552-6259</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtrGzEURkVJSB23_6AFLUJIFtNKo8dIm0Jj8igEuknXQiNdYZV5ONKMQ_595NgkuyCErrjnu1wOQt8o-UEJlT8JIaziuhEXur7UhAtWXX1CCypEXcla6CO0eEM-o9Oc_5dvXdon6IQKSkQtFuhhZZOP1uGt7baAE2w666CHYcJxwBs7xVLmUgdwE3j8FKc1ntaA13NvBxz7fh5GDyG6ArpnvI1pzl_QcbBdhq-Hd4n-3Vw_rO6q-7-3f1a_7yvHZTNVioVAefC727QqBC-BCqYgWK6I18ClFqrlqiVSKeobxZl3RNatKzlXsyU638_dpPFxhjyZPmYHXWcHGOdsGkYl0-UsEd-DLo05Jwhmk2Jv07OhxOxkmp0pszNldG1eZZqrEvt-mD-3Pfj30N5e6Z8d-jY724VkBxfzGyaEFEzTgv3aY1BcbCMkk19tgY-pWDV-jB_v8QL175EQ</recordid><startdate>19920901</startdate><enddate>19920901</enddate><creator>Bräu, Norbert</creator><creator>Esposito, Rick A.</creator><creator>Simberkoff, Michael S.</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19920901</creationdate><title>Cardiac valve replacement in patients infected with the human immunodeficiency virus</title><author>Bräu, Norbert ; Esposito, Rick A. ; Simberkoff, Michael S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c467t-83ff14fd14fd7b8ffd6e1538efa480d9e46958b48b06881d7843dc062bcf14c23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Adult</topic><topic>AIDS/HIV</topic><topic>Biological and medical sciences</topic><topic>Bioprosthesis</topic><topic>Endocarditis, Bacterial - complications</topic><topic>Endocarditis, Bacterial - surgery</topic><topic>Heart Valve Diseases - complications</topic><topic>Heart Valve Diseases - surgery</topic><topic>Heart Valve Prosthesis</topic><topic>HIV Infections - complications</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the heart</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bräu, Norbert</creatorcontrib><creatorcontrib>Esposito, Rick A.</creatorcontrib><creatorcontrib>Simberkoff, Michael S.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bräu, Norbert</au><au>Esposito, Rick A.</au><au>Simberkoff, Michael S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cardiac valve replacement in patients infected with the human immunodeficiency virus</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>1992-09-01</date><risdate>1992</risdate><volume>54</volume><issue>3</issue><spage>552</spage><epage>554</epage><pages>552-554</pages><issn>0003-4975</issn><eissn>1552-6259</eissn><coden>ATHSAK</coden><abstract>Major surgical procedures, especially when performed under general anesthesia, can depress immunological parameters measured in vitro. Therefore concern has been expressed that operation might have an adverse effect on the immune status of individuals infected with the human immunodeficiency virus (HIV). Four HIV-positive patients without symptoms of HIV disease underwent cardiac valve replacement in consequence of infective endocarditis. After up to 15 months postoperalively, 3 patients are alive and well without signs of progressive immunodeficiency or recurrent endocarditis. One patient died of recurrent endocarditis without evidence of HIV-related disease on autopsy. Cardiac operation does not seem to accelerate HIV-related immunodeficiency.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>1510525</pmid><doi>10.1016/0003-4975(92)90453-B</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult AIDS/HIV Biological and medical sciences Bioprosthesis Endocarditis, Bacterial - complications Endocarditis, Bacterial - surgery Heart Valve Diseases - complications Heart Valve Diseases - surgery Heart Valve Prosthesis HIV Infections - complications Humans Male Medical sciences Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart |
title | Cardiac valve replacement in patients infected with the human immunodeficiency virus |
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