Modulation of muscle insulin resistance by selective inhibition of GSK-3 in Zucker diabetic fatty rats

1 Muscle Metabolism Laboratory, Department of Physiology, University of Arizona College of Medicine, Tucson, Arizona 85721; and 2 Chiron Corporation, Emeryville, California 94608 A role for elevated glycogen synthase kinase-3 (GSK-3) activity in the multifactorial etiology of insulin resistance is...

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Veröffentlicht in:	American journal of physiology: endocrinology and metabolism 2003-05, Vol.284 (5), p.E892-E900
Hauptverfasser:	Henriksen, Erik J, Kinnick, Tyson R, Teachey, Mary K, O'Keefe, Matthew P, Ring, David, Johnson, Kirk W, Harrison, Stephen D
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Biological Transport - drug effects Blood Glucose - drug effects Blood Glucose - metabolism Cell Membrane - metabolism Diabetes Mellitus - metabolism Enzyme Inhibitors - pharmacology Glucose - metabolism Glucose Transporter Type 4 Glycogen Synthase - metabolism Glycogen Synthase Kinase 3 - metabolism Insulin Resistance Lithium - pharmacology Male Monosaccharide Transport Proteins - metabolism Muscle Proteins Muscle, Skeletal - metabolism Obesity Rats Rats, Zucker
Online-Zugang:	Volltext
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