Induction of long-term remission of a relapsed Childhood B-acute lymphoblastic leukemia with rituximab chimeric anti-CD20 monoclonal antibody and autologous stem cell transplantation

Childhood B-cell neoplasms account for approximately 2% of childhood acute lymphoblastic leukemia (ALL). The short but intensive chemotherapy yields a currently 75% to 85% event-free survival. The prognosis for children with relapsed disease is considered to be dismal. We report a 12-year old boy di...

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Veröffentlicht in:	Journal of pediatric hematology/oncology 2003-04, Vol.25 (4), p.327-329
Hauptverfasser:	CORBACIOGLU, Selim, EBER, Stefan, GUNGOR, Tayfun, HUMMERJOHANN, Jorg, NIGGLI, Felix
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal - therapeutic use Antibodies, Monoclonal, Murine-Derived Antigens, CD20 - immunology Antigens, Neoplasm - immunology Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Bone Marrow Purging Burkitt Lymphoma - drug therapy Burkitt Lymphoma - therapy Child Combined Modality Therapy Cytarabine - administration & dosage Dexamethasone - administration & dosage Etoposide - administration & dosage Hematologic and hematopoietic diseases Humans Immunotherapy Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Leukemic Infiltration - drug therapy Leukemic Infiltration - therapy Male Medical sciences Meninges - pathology Methotrexate - administration & dosage Peripheral Blood Stem Cell Transplantation Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy Prednisone - administration & dosage Recurrence Remission Induction Rituximab Salvage Therapy Testis - pathology Topotecan - administration & dosage Transplantation, Autologous Vindesine - administration & dosage
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