The K1 capsule modulates trafficking of E. coli‐containing vacuoles and enhances intracellular bacterial survival in human brain microvascular endothelial cells

Summary Escherichia coli K1 has been shown to invade human brain microvascular endothelial cells (HBMEC) in vitro and translocate the blood–brain barrier in vivo, but it is unclear how E. coli K1 traverses HBMEC. We have previously shown that internalized E. coli K1 is localized within membrane‐boun...

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Veröffentlicht in:	Cellular microbiology 2003-04, Vol.5 (4), p.245-252
Hauptverfasser:	Kim, Kee Jun, Elliott, Simon Justin, Di Cello, Francescopaolo, Stins, Monique Fabienne, Kim, Kwang Sik
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Bacterial - metabolism Bacterial Capsules - metabolism Bacterial Capsules - ultrastructure Biological Transport - physiology Blood-Brain Barrier - physiology Brain - cytology Brain - microbiology Cell Line Endocytosis - physiology Endothelium, Vascular - cytology Endothelium, Vascular - microbiology Epitopes Escherichia coli - metabolism Escherichia coli - ultrastructure Humans Lysosomes - metabolism Polysaccharides, Bacterial - metabolism Vacuoles - metabolism
Online-Zugang:	Volltext
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