The relationship between the concentration of temazepam in cerebrospinal fluid and sedation in man

Summary Twenty‐six patients received oral temazepam and subsequently spinal anaesthesia. Blood and lumbar cerebrospinal fluid temazepam levels were measured together with the degree of sedation. The plasma and cerebrospinal fluid concentrations correlated well with the temazepam dose but even better...

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Veröffentlicht in:Anaesthesia 1992-04, Vol.47 (4), p.303-306
Hauptverfasser: OSBORNE, G. A., BADCOCK, N. R., McGRATH, P. M., RUSSELL, W. J., FREWIN, D. B.
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Sprache:eng
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