Defective organization of the erythroid cell membrane in a novel case of congenital anemia

In the present paper, we demonstrate the erythroid cell membrane unique properties in a previously characterized case of hemoglobin-H disease, associated with congenital dyserythropoietic anemia type-I features. In order to explain the patient’s cell membrane distortions and the high affinity for th...

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Veröffentlicht in:	Blood cells, molecules, & diseases molecules, & diseases, 2003, Vol.30 (1), p.43-54
Hauptverfasser:	Antonelou, Marianna H, Papassideri, Issidora S, Karababa, Fotini J, Stravopodis, Dimitrios J, Loutradi, Afroditi, Margaritis, Lukas H
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Thalassemia - complications alpha-Thalassemia - pathology Anemia, Dyserythropoietic, Congenital - complications Anemia, Dyserythropoietic, Congenital - pathology Blotting, Western Bone Marrow Cells - metabolism Bone Marrow Cells - pathology Bone Marrow Cells - ultrastructure Electrophoresis, Polyacrylamide Gel Erythrocyte Membrane - metabolism Erythrocyte Membrane - pathology Erythrocyte Membrane - ultrastructure Erythrocytes - metabolism Erythrocytes - pathology Erythrocytes - ultrastructure Erythroid Precursor Cells - metabolism Erythroid Precursor Cells - pathology Erythroid Precursor Cells - ultrastructure Globins - analysis Glycophorin - analysis Humans Immunoglobulins - immunology Immunohistochemistry Membrane Proteins - metabolism Microscopy, Electron Spectrin - analysis
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