Disruption of ovarian development in alligator embryos treated with an aromatase inhibitor

It has been suggested that sex differentiation in vertebrates is steroid hormone dependent, that estrogens play a critical role in ovarian differentiation, and that male sex differentiation will occur in the absence of estrogens. Using the model of the alligator in which sex can be manipulated by in...

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Veröffentlicht in:	General and comparative endocrinology 1992-04, Vol.86 (1), p.59-71
Hauptverfasser:	Lance, Valentine A., Bogart, Mark H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alligator Alligators and Crocodiles - embryology Aminoglutethimide - pharmacology Androstenedione - analogs & derivatives Androstenedione - pharmacology Animals Aromatase Inhibitors Biological and medical sciences Cyproterone - analogs & derivatives Cyproterone - pharmacology Cyproterone Acetate Embryology: invertebrates and vertebrates. Teratology Estradiol - pharmacology Experimental organogenesis Fadrozole Female Freshwater Fundamental and applied biological sciences. Psychology Imidazoles - pharmacology Male Nitriles - pharmacology Organogenesis. Physiological fonctions Ovary - drug effects Ovary - embryology Tamoxifen - pharmacology Testis - drug effects Testis - embryology
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