Reduction of flurazepam's antiseizure efficacy persists after stress

Twenty-four hours after mice were forced to swim for up to 10 min in cold (6°C) water, the ability of flurazepam to antagonize the electrical precipitation of seizures was reduced. This stress-induced reduction in flurazepam's antiseizure efficacy persisted for at least 72 h; but was absent 1 w...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 1992-08, Vol.42 (4), p.681-684
Hauptverfasser:	Mastropaolo, John, Park, Chan H., Norris, Deborah Olin, O'Connor, David A., Lukacs, Lorinc G., Deutsch, Stephen I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticonvulsants - pharmacology Anticonvulsants. Antiepileptics. Antiparkinson agents Biological and medical sciences Cold Temperature Electroshock Flurazepam Flurazepam - pharmacology Male Medical sciences Mice Neuropharmacology Pharmacology. Drug treatments Seizures Seizures - physiopathology Seizures - prevention & control Stress Stress, Psychological - physiopathology Swimming
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!