Elevated soluble c-erbB-2 antigen levels in the serum and effusions of a proportion of breast cancer patients

An enzyme-linked immunosorbent assay (ELISA) for the extracellular domain of the c-erbB-2 oncogene product was developed and evaluated to determine if soluble c-erbB-2 could be detected in the serum and effusions of cancer patients. Sera from 208 previously untreated or progressing cancer patients a...

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Veröffentlicht in:	Journal of clinical oncology 1992-09, Vol.10 (9), p.1436-1443
Hauptverfasser:	LEITZEL, K, TERAMOTO, Y, WEAVER, S, LIPTON, A, SAMPSON, E, MAUCERI, J, LANGTON, B. C, DEMERS, L, PODCZASKI, E, HARVEY, H, SHAMBAUGH, S, VOLAS, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antigens, Neoplasm - blood Antigens, Neoplasm - metabolism Biological and medical sciences Biomarkers, Tumor - metabolism Blotting, Western Breast Neoplasms - blood Breast Neoplasms - metabolism Enzyme-Linked Immunosorbent Assay Extracellular Space - metabolism Female Gynecology. Andrology. Obstetrics Humans Male Mammary gland diseases Medical sciences Middle Aged Precipitin Tests Proto-Oncogene Proteins - metabolism Proto-Oncogenes - physiology Radioimmunoprecipitation Assay Receptor, ErbB-2 Receptors, Cell Surface - metabolism Solubility Tumors
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