Structure and function of archaeal box C/D sRNP core proteins

Nop56p and Nop58p are two core proteins of the box C/D snoRNPs that interact concurrently with fibrillarin and snoRNAs to function in enzyme assembly and catalysis. Here we report the 2.9 Å resolution co-crystal structure of an archaeal homolog of Nop56p/Nop58p, Nop5p, in complex with fibrillarin fr...

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Veröffentlicht in:	Nature Structural Biology 2003-04, Vol.10 (4), p.256-263
Hauptverfasser:	Aittaleb, Mohamed, Rashid, Rumana, Chen, Qiong, Palmer, John R., Daniels, Charles J., Li, Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Archaeal Proteins - chemistry Archaeal Proteins - genetics Archaeal Proteins - metabolism Archaeoglobus fulgidus - genetics Archaeoglobus fulgidus - metabolism BASIC BIOLOGICAL SCIENCES Binding Sites Biochemistry BIOLOGICAL FUNCTIONS Biological Microscopy Biomedical and Life Sciences Catalysis Chromosomal Proteins, Non-Histone - chemistry Chromosomal Proteins, Non-Histone - metabolism Crystallography, X-Ray Dimerization Electrophoretic Mobility Shift Assay Life Sciences Macromolecular Substances Membrane Biology Models, Molecular Molecular Sequence Data Molecular Structure NATIONAL SYNCHROTRON LIGHT SOURCE Nuclear Proteins PROTEIN STRUCTURE Protein Structure, Tertiary PROTEINS Ribonucleoproteins, Small Nucleolar - chemistry Ribonucleoproteins, Small Nucleolar - genetics Ribonucleoproteins, Small Nucleolar - metabolism RNA Editing RNA, Archaeal - chemistry RNA, Archaeal - genetics RNA, Archaeal - metabolism RNA, Guide - chemistry RNA, Guide - genetics RNA, Guide - metabolism RNA, Small Nucleolar - chemistry RNA, Small Nucleolar - genetics RNA, Small Nucleolar - metabolism Sequence Homology, Amino Acid Static Electricity Structural analysis
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