Prevention of adjuvant arthritis by cyclosporine in rats

The effect of cyclosporine A during the development phase of adjuvant arthritis was studied in 40 female rats. Five groups of eight animals each received oral cyclosporine, 2.5, 5, 10, 20, or 30 mg/kg daily for 30 days. Also, eight normal and eight diseased rats served as placebo controls. At the ti...

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Veröffentlicht in:	Seminars in arthritis and rheumatism 1992-06, Vol.21 (6), p.23-29
Hauptverfasser:	del Pozo, Emilio, Elford, Peter, Perrelet, Romain, Graeher, Michael, Casez, Jean Paul, Modrowski, Dominique, Payne, Trevor, MacKenzie, Roland
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arthritis, Experimental - prevention & control Bone and Bones - metabolism Bone Density Calcium - metabolism Cartilage - chemistry Cyclosporine - pharmacology Edema - prevention & control Female Foot Osteocalcin - blood Rats Spine - metabolism Spine - pathology
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