An Autopsy Case of Endocardial Cushion Defect (ECD) in an 82-Year-Old Female
In an 82-year-old female case of endocardial cushion defect (ECD), a systolic regurgitant murmur was heard at the apex, and her ECG showed atrial fibrillation without right bundle branch block or left axis deviation. An echocardiogram demonstrated atrial septal defect (ASD) and a cleft of the anteri...
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| Veröffentlicht in: | Nihon Rōnen Igakkai zasshi 1992/05/25, Vol.29(5), pp.416-422 |
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| container_title | Nihon Rōnen Igakkai zasshi |
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| creator | Matsumoto, Yoshihisa Ueda, Seigo Tsukazaki, Tomio Katou, Youichi Maeda, Shigeru Sakai, Makoto Kuwajima, Iwao Ohkawa, Shin-ichiro Matsushita, Satoru Ueda, Keiji Kuramoto, Kizuku Inoue, Yasushi Shimada, Hiroyuki |
| description | In an 82-year-old female case of endocardial cushion defect (ECD), a systolic regurgitant murmur was heard at the apex, and her ECG showed atrial fibrillation without right bundle branch block or left axis deviation. An echocardiogram demonstrated atrial septal defect (ASD) and a cleft of the anterior mitral leaflet with calcification. She died of refractory congestive heart failure. Autopsy revealed ECD (intermediate type) with mitral and tricuspid cleft, and ASD (ostium primum type, 2.0×1.0cm in diameter). In addition, mitral ring calcification and calcification of the cleft mitral valve was disclosed, causing mitral stenosis in addition to mitral regurgitation due to the cleft mitral valve. This was the second oldest Japanese autopsy case of ECD. We concluded that echocardiographic examinations, including color flow imaging, in aged patients with heart murmur are necessary to confirm the diagnosis of congenital heart disease in the aged. |
| doi_str_mv | 10.3143/geriatrics.29.416 |
| format | Article |
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An echocardiogram demonstrated atrial septal defect (ASD) and a cleft of the anterior mitral leaflet with calcification. She died of refractory congestive heart failure. Autopsy revealed ECD (intermediate type) with mitral and tricuspid cleft, and ASD (ostium primum type, 2.0×1.0cm in diameter). In addition, mitral ring calcification and calcification of the cleft mitral valve was disclosed, causing mitral stenosis in addition to mitral regurgitation due to the cleft mitral valve. This was the second oldest Japanese autopsy case of ECD. We concluded that echocardiographic examinations, including color flow imaging, in aged patients with heart murmur are necessary to confirm the diagnosis of congenital heart disease in the aged.</description><identifier>ISSN: 0300-9173</identifier><identifier>DOI: 10.3143/geriatrics.29.416</identifier><identifier>PMID: 1507514</identifier><language>jpn</language><publisher>Japan: The Japan Geriatrics Society</publisher><subject>Aged ; Aged, 80 and over ; Atrial septal defect (ASD) ; Color flow imaging ; Echocardiogram ; Echocardiography ; Endocardial cushion defect (ECD) ; Endocardial Cushion Defects - diagnostic imaging ; Endocardial Cushion Defects - pathology ; Female ; Heart Septal Defects, Atrial - pathology ; Humans ; Mitral and tricuspid cleft ; Mitral Valve - abnormalities ; Tricuspid Valve - abnormalities</subject><ispartof>Nippon Ronen Igakkai Zasshi. 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An echocardiogram demonstrated atrial septal defect (ASD) and a cleft of the anterior mitral leaflet with calcification. She died of refractory congestive heart failure. Autopsy revealed ECD (intermediate type) with mitral and tricuspid cleft, and ASD (ostium primum type, 2.0×1.0cm in diameter). In addition, mitral ring calcification and calcification of the cleft mitral valve was disclosed, causing mitral stenosis in addition to mitral regurgitation due to the cleft mitral valve. This was the second oldest Japanese autopsy case of ECD. We concluded that echocardiographic examinations, including color flow imaging, in aged patients with heart murmur are necessary to confirm the diagnosis of congenital heart disease in the aged.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Atrial septal defect (ASD)</subject><subject>Color flow imaging</subject><subject>Echocardiogram</subject><subject>Echocardiography</subject><subject>Endocardial cushion defect (ECD)</subject><subject>Endocardial Cushion Defects - diagnostic imaging</subject><subject>Endocardial Cushion Defects - pathology</subject><subject>Female</subject><subject>Heart Septal Defects, Atrial - pathology</subject><subject>Humans</subject><subject>Mitral and tricuspid cleft</subject><subject>Mitral Valve - abnormalities</subject><subject>Tricuspid Valve - abnormalities</subject><issn>0300-9173</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkL1PwzAQxT2AChT-AAYkTwiGFH_FrscqLV-q1AUGJuvqXCBVmhQ7GfrfkyqIstwN772f7h4h15xNJFfy4RNDCW0ofZwIO1Fcn5BzJhlLLDfyjFzEuGEsTZUWIzLiKTMpV-dkOavprGubXdzTDCLSpqCLOm88hLyEimZd_Cqbms6xQN_Su0U2v6dlTaGmU5F8IIRkVeX0EbdQ4SU5LaCKePW7x-T9cfGWPSfL1dNLNlsmXpqpTiyzTDBtYM0VtwZQKuivQYV6yvMiT0UuuNVFoYXBaVpYb9dGcC4ER9Ao5ZjcDtxdaL47jK3bltFjVUGNTRedkVwqa0xv5IPRhybGgIXbhXILYe84c4fW3LE1J6zrW-szN7_wbr3F_JgYKuv110HfxBY-8U-H0Ja-wn_E_gd1oKbD6OF_Jv8FwWEtfwDUSYRp</recordid><startdate>1992</startdate><enddate>1992</enddate><creator>Matsumoto, Yoshihisa</creator><creator>Ueda, Seigo</creator><creator>Tsukazaki, Tomio</creator><creator>Katou, Youichi</creator><creator>Maeda, Shigeru</creator><creator>Sakai, Makoto</creator><creator>Kuwajima, Iwao</creator><creator>Ohkawa, Shin-ichiro</creator><creator>Matsushita, Satoru</creator><creator>Ueda, Keiji</creator><creator>Kuramoto, Kizuku</creator><creator>Inoue, Yasushi</creator><creator>Shimada, Hiroyuki</creator><general>The Japan Geriatrics Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1992</creationdate><title>An Autopsy Case of Endocardial Cushion Defect (ECD) in an 82-Year-Old Female</title><author>Matsumoto, Yoshihisa ; Ueda, Seigo ; Tsukazaki, Tomio ; Katou, Youichi ; Maeda, Shigeru ; Sakai, Makoto ; Kuwajima, Iwao ; Ohkawa, Shin-ichiro ; Matsushita, Satoru ; Ueda, Keiji ; Kuramoto, Kizuku ; Inoue, Yasushi ; Shimada, Hiroyuki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3786-90902067ab14197ae34a751e4e681dfd52d2196ff627e85f9c9b7211221ea6e33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>jpn</language><creationdate>1992</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Atrial septal defect (ASD)</topic><topic>Color flow imaging</topic><topic>Echocardiogram</topic><topic>Echocardiography</topic><topic>Endocardial cushion defect (ECD)</topic><topic>Endocardial Cushion Defects - diagnostic imaging</topic><topic>Endocardial Cushion Defects - pathology</topic><topic>Female</topic><topic>Heart Septal Defects, Atrial - pathology</topic><topic>Humans</topic><topic>Mitral and tricuspid cleft</topic><topic>Mitral Valve - abnormalities</topic><topic>Tricuspid Valve - abnormalities</topic><toplevel>online_resources</toplevel><creatorcontrib>Matsumoto, Yoshihisa</creatorcontrib><creatorcontrib>Ueda, Seigo</creatorcontrib><creatorcontrib>Tsukazaki, Tomio</creatorcontrib><creatorcontrib>Katou, Youichi</creatorcontrib><creatorcontrib>Maeda, Shigeru</creatorcontrib><creatorcontrib>Sakai, Makoto</creatorcontrib><creatorcontrib>Kuwajima, Iwao</creatorcontrib><creatorcontrib>Ohkawa, Shin-ichiro</creatorcontrib><creatorcontrib>Matsushita, Satoru</creatorcontrib><creatorcontrib>Ueda, Keiji</creatorcontrib><creatorcontrib>Kuramoto, Kizuku</creatorcontrib><creatorcontrib>Inoue, Yasushi</creatorcontrib><creatorcontrib>Shimada, Hiroyuki</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Nihon Rōnen Igakkai zasshi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Matsumoto, Yoshihisa</au><au>Ueda, Seigo</au><au>Tsukazaki, Tomio</au><au>Katou, Youichi</au><au>Maeda, Shigeru</au><au>Sakai, Makoto</au><au>Kuwajima, Iwao</au><au>Ohkawa, Shin-ichiro</au><au>Matsushita, Satoru</au><au>Ueda, Keiji</au><au>Kuramoto, Kizuku</au><au>Inoue, Yasushi</au><au>Shimada, Hiroyuki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An Autopsy Case of Endocardial Cushion Defect (ECD) in an 82-Year-Old Female</atitle><jtitle>Nihon Rōnen Igakkai zasshi</jtitle><addtitle>Nippon Ronen Igakkai Zasshi</addtitle><date>1992</date><risdate>1992</risdate><volume>29</volume><issue>5</issue><spage>416</spage><epage>422</epage><pages>416-422</pages><issn>0300-9173</issn><abstract>In an 82-year-old female case of endocardial cushion defect (ECD), a systolic regurgitant murmur was heard at the apex, and her ECG showed atrial fibrillation without right bundle branch block or left axis deviation. An echocardiogram demonstrated atrial septal defect (ASD) and a cleft of the anterior mitral leaflet with calcification. She died of refractory congestive heart failure. Autopsy revealed ECD (intermediate type) with mitral and tricuspid cleft, and ASD (ostium primum type, 2.0×1.0cm in diameter). In addition, mitral ring calcification and calcification of the cleft mitral valve was disclosed, causing mitral stenosis in addition to mitral regurgitation due to the cleft mitral valve. This was the second oldest Japanese autopsy case of ECD. We concluded that echocardiographic examinations, including color flow imaging, in aged patients with heart murmur are necessary to confirm the diagnosis of congenital heart disease in the aged.</abstract><cop>Japan</cop><pub>The Japan Geriatrics Society</pub><pmid>1507514</pmid><doi>10.3143/geriatrics.29.416</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 1992/05/25, Vol.29(5), pp.416-422 |
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| subjects | Aged Aged, 80 and over Atrial septal defect (ASD) Color flow imaging Echocardiogram Echocardiography Endocardial cushion defect (ECD) Endocardial Cushion Defects - diagnostic imaging Endocardial Cushion Defects - pathology Female Heart Septal Defects, Atrial - pathology Humans Mitral and tricuspid cleft Mitral Valve - abnormalities Tricuspid Valve - abnormalities |
| title | An Autopsy Case of Endocardial Cushion Defect (ECD) in an 82-Year-Old Female |
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