Effect of topically applied basic fibroblast growth factor on injured cochlear nerve

Trauma-induced hearing loss after cerebellopontine angle manipulation has been regarded as having a hopeless natural course once it occurs. To challenge such a pessimistic view, we investigated whether pharmacological interventions with basic fibroblast growth factor (bFGF) could ameliorate trauma-i...

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Veröffentlicht in:	Neurosurgery 2003-04, Vol.52 (4), p.900-907
Hauptverfasser:	Sekiya, Tetsuji, Shimamura, Norihito, Yagihashi, Akinori, Suzuki, Shigeharu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Count Cell Death - drug effects Cochlear Nerve - injuries Cochlear Nerve - pathology Drug Implants Fibroblast Growth Factor 2 - pharmacology Infusion Pumps, Implantable Male Nerve Crush Nerve Degeneration - pathology Nerve Regeneration - drug effects Rats Rats, Sprague-Dawley Spiral Ganglion - drug effects Spiral Ganglion - pathology
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