Investigating the role of dopaminergic and serotonergic candidate genes in obsessive-compulsive disorder

There is increasing evidence that the aetiology of obsessive-compulsive disorder (OCD) has a marked genetic component, although the precise mechanism of inheritance is unclear. Clinical and pharmacological studies have implicated the serotonergic and dopaminergic systems in disease pathogenesis. Thi...

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Veröffentlicht in:	European neuropsychopharmacology 2003-03, Vol.13 (2), p.93-98
Hauptverfasser:	Hemmings, Sı&#x0302, an M.J., Kinnear, Craig J., Niehaus, Dana J.H., Moolman-Smook, Johanna C., Lochner, Christine, Knowles, James A., Corfield, Valerie A., Stein, Dan J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Afrikaner Association studies Case-Control Studies Chi-Square Distribution Dopamine - genetics Dopamine Plasma Membrane Transport Proteins Gene Frequency - genetics Genetics Humans Membrane Glycoproteins Membrane Transport Proteins - genetics Monoamine Oxidase - genetics Nerve Tissue Proteins Obsessive-compulsive disorder Obsessive-Compulsive Disorder - genetics Polymorphism, Genetic - genetics Receptor, Serotonin, 5-HT1B Receptor, Serotonin, 5-HT2A Receptors, Dopamine D2 - genetics Receptors, Dopamine D4 Receptors, Serotonin - genetics Serotonin - genetics
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