Chromosomal Cohesin Forms a Ring

The cohesin complex is essential for sister chromatid cohesion during mitosis. Its Smc1 and Smc3 subunits are rod-shaped molecules with globular ABC-like ATPases at one end and dimerization domains at the other connected by long coiled coils. Smc1 and Smc3 associate to form V-shaped heterodimers. Th...

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Veröffentlicht in:	Cell 2003-03, Vol.112 (6), p.765-777
Hauptverfasser:	Gruber, Stephan, Haering, Christian H, Nasmyth, Kim
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Anaphase Binding Sites Cell Cycle Proteins - drug effects Cell Cycle Proteins - metabolism Chondroitin Sulfate Proteoglycans Chromatids - physiology Chromatin - physiology Chromosomal Proteins, Non-Histone - metabolism Chromosomes, Fungal - chemistry Cohesins Conserved Sequence Dimerization DNA-Binding Proteins - chemistry DNA-Binding Proteins - metabolism Fungal Proteins - chemistry Fungal Proteins - metabolism Molecular Sequence Data Nuclear Proteins - chemistry Nuclear Proteins - metabolism Phosphoproteins - metabolism Protein Structure, Tertiary Protein Subunits - chemistry Saccharomyces cerevisiae Proteins Schizosaccharomyces pombe Proteins - metabolism Sequence Homology, Amino Acid Yeasts
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