The effect of bone marrow stromal cells on neuronal differentiation of mesencephalic neural stem cells in Sprague–Dawley rats

There are numerous parallels between the heamatolymphopoietic and nervous systems in terms of the mechanisms regulating their development. We proposed that neural stem cells (NSCs) may respond to the microenvironmental signals provided by bone marrow stromal cells (BMSCs) which regulate the differen...

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Veröffentlicht in:	Brain research 2003-04, Vol.968 (1), p.114-121
Hauptverfasser:	Lou, Shu-jie, Gu, Ping, Chen, Fei, He, Cheng, Wang, Ming-wei, Lu, Chang-lin
Format:	Artikel
Sprache:	eng
Schlagworte:	2',3'-Cyclic-Nucleotide Phosphodiesterases - metabolism Animals Animals, Newborn Antigens, CD - metabolism Antigens, Differentiation, B-Lymphocyte - metabolism Bone Marrow Cells - cytology Bone marrow stromal cell Cell Count Cell Differentiation - drug effects Cell Differentiation - physiology Cell Membrane - metabolism Cell Survival Cells, Cultured Coculture Techniques Culture Media, Conditioned - pharmacology Differentiation Glial Fibrillary Acidic Protein - metabolism Immunochemistry Intermediate Filament Proteins - metabolism Mesencephalon - cytology Microtubule-Associated Proteins - metabolism Nerve Tissue Proteins Nestin Neural stem cell Neuron Neurons - cytology Neurons - drug effects Neurons - physiology Rats Rats, Sprague-Dawley - growth & development Rats, Sprague-Dawley - metabolism Receptors, Transferrin Stem Cells - cytology Stem Cells - physiology Stromal Cells - metabolism Stromal Cells - physiology Time Factors
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