Windows into development: historic, current, and future perspectives on transgenic zebrafish

The recent explosion of transgenic zebrafish lines in the literature demonstrates the value of this model system for detailed in vivo analysis of gene regulation and morphogenetic movements. The optical clarity and rapid early development of zebrafish provides the ability to follow these events as t...

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Veröffentlicht in:Developmental Biology 2003-04, Vol.256 (1), p.1-17
Hauptverfasser: Udvadia, Ava J, Linney, Elwood
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description The recent explosion of transgenic zebrafish lines in the literature demonstrates the value of this model system for detailed in vivo analysis of gene regulation and morphogenetic movements. The optical clarity and rapid early development of zebrafish provides the ability to follow these events as they occur in live, developing embryos. This article will review the development of transgenic technology in zebrafish as well as the current and future uses of transgenic zebrafish to explore the dynamic environment of the developing vertebrate embryo.
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subjects Animals
Animals, Genetically Modified
Danio rerio
Developmental Biology - history
Developmental Biology - trends
Female
Freshwater
Gene Expression Regulation, Developmental
Gene regulation
Gene Targeting - history
Gene Targeting - trends
Genetic Engineering - history
Genetic Engineering - trends
History, 20th Century
History, 21st Century
Male
Time-lapse
Transgenic
transgenic fish
Zebrafish
Zebrafish - embryology
Zebrafish - genetics
title Windows into development: historic, current, and future perspectives on transgenic zebrafish
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