Windows into development: historic, current, and future perspectives on transgenic zebrafish
The recent explosion of transgenic zebrafish lines in the literature demonstrates the value of this model system for detailed in vivo analysis of gene regulation and morphogenetic movements. The optical clarity and rapid early development of zebrafish provides the ability to follow these events as t...
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Veröffentlicht in: | Developmental Biology 2003-04, Vol.256 (1), p.1-17 |
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description | The recent explosion of transgenic zebrafish lines in the literature demonstrates the value of this model system for detailed in vivo analysis of gene regulation and morphogenetic movements. The optical clarity and rapid early development of zebrafish provides the ability to follow these events as they occur in live, developing embryos. This article will review the development of transgenic technology in zebrafish as well as the current and future uses of transgenic zebrafish to explore the dynamic environment of the developing vertebrate embryo. |
doi_str_mv | 10.1016/S0012-1606(02)00083-0 |
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source | MEDLINE; ScienceDirect Journals (5 years ago - present); EZB-FREE-00999 freely available EZB journals |
subjects | Animals Animals, Genetically Modified Danio rerio Developmental Biology - history Developmental Biology - trends Female Freshwater Gene Expression Regulation, Developmental Gene regulation Gene Targeting - history Gene Targeting - trends Genetic Engineering - history Genetic Engineering - trends History, 20th Century History, 21st Century Male Time-lapse Transgenic transgenic fish Zebrafish Zebrafish - embryology Zebrafish - genetics |
title | Windows into development: historic, current, and future perspectives on transgenic zebrafish |
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