Sigma receptors in schizophrenic cerebral cortices

Antipsychotics represent high affinity for sigma receptors and sigma-like drugs often have the psychotomimetic properties. Besides, the receptors are unevenly distributed in human brain. These findings suggest that sigma receptors might be involved in the pathophysiology of schizophrenia. Sigma rece...

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Veröffentlicht in:	Neurochemical research 1992-10, Vol.17 (10), p.983-990
Hauptverfasser:	SHIBUYA, H, MORI, H, TORU, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult and adolescent clinical studies Aged Amino Acids - pharmacology Animals Biological and medical sciences Cations - pharmacology Cerebral Cortex - chemistry Cerebral Cortex - drug effects cerebrum cortex Female Guanidines - metabolism Humans Male Medical sciences Middle Aged Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Radioligand Assay Rats Rats, Inbred Strains Receptors, Opioid - analysis Receptors, sigma schizophrenia Schizophrenia - metabolism
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