Penicillin derived C2-symmetric dimers as novel inhibitors of HIV-1 proteinase
Gespeichert in:
| Veröffentlicht in: | Journal of medicinal chemistry 1992-08, Vol.35 (16), p.3080-3081 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 3081 |
|---|---|
| container_issue | 16 |
| container_start_page | 3080 |
| container_title | Journal of medicinal chemistry |
| container_volume | 35 |
| creator | Humber, David C Cammack, Nicholas Coates, Jonathan A. V Cobley, Kevin N Orr, David C Storer, Richard Weingarten, Gordon G Weir, Malcolm P |
| description | |
| doi_str_mv | 10.1021/jm00094a024 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_73123219</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>73123219</sourcerecordid><originalsourceid>FETCH-LOGICAL-a298t-6a8da908a4cdcf23c437efd6207d328bd182397957b03089335da055ebba57bc3</originalsourceid><addsrcrecordid>eNptkE1PGzEQhi1UlIa0J86V9lCVA1oY27vZ3WMVAYmKQqSmXK1Ze1Z1uh_B3iDy73G0EfTAaax5H82MH8bOOVxxEPx60wBAkSCI5ISNeSogTnJIPrExgBCxmAr5mZ15vwmY5EKO2IinEB7pmC1X1Fpt69q2kSFnn8lEMxH7fdNQ76yOjG3I-Qh91HbPVEe2_WtL23eh11XRfPEY82jrup5si56-sNMKa09fj3XC_tzerGfz-P7hbjH7eR-jKPI-nmJusIAcE210JaROZEaVmQrIjBR5aXguZJEVaVaChLyQMjUIaUpliaGn5YT9GOaG1U878r1qrNdU19hSt_MqO_xT8CKAlwOoXee9o0ptnW3Q7RUHdbCn_rMX6G_HsbuyIfPODrpC_v2Yo9dYVw5bbf0blsicH2xPWDxg1vf08haj-6emmcxStV79Vr-SRznPipVaBv5i4FF7tel2rg3uPjzwFYvAkRE</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>73123219</pqid></control><display><type>article</type><title>Penicillin derived C2-symmetric dimers as novel inhibitors of HIV-1 proteinase</title><source>MEDLINE</source><source>ACS Publications</source><creator>Humber, David C ; Cammack, Nicholas ; Coates, Jonathan A. V ; Cobley, Kevin N ; Orr, David C ; Storer, Richard ; Weingarten, Gordon G ; Weir, Malcolm P</creator><creatorcontrib>Humber, David C ; Cammack, Nicholas ; Coates, Jonathan A. V ; Cobley, Kevin N ; Orr, David C ; Storer, Richard ; Weingarten, Gordon G ; Weir, Malcolm P</creatorcontrib><identifier>ISSN: 0022-2623</identifier><identifier>EISSN: 1520-4804</identifier><identifier>DOI: 10.1021/jm00094a024</identifier><identifier>PMID: 1501235</identifier><identifier>CODEN: JMCMAR</identifier><language>eng</language><publisher>Washington, DC: American Chemical Society</publisher><subject>AIDS/HIV ; Antiviral Agents - pharmacology ; Cell Line ; Chemistry ; Cytopathogenic Effect, Viral - drug effects ; Dioxoles - pharmacology ; Dioxoles - therapeutic use ; Exact sciences and technology ; Heterocyclic compounds ; Heterocyclic compounds with n hetero atom and also o and/or s, se, te hetero atoms ; HIV Protease Inhibitors ; HIV-1 - drug effects ; HIV-1 - enzymology ; HIV-1 - physiology ; Humans ; Organic chemistry ; Penicillins - pharmacology ; Preparations and properties ; Virus Replication - drug effects ; X-Ray Diffraction</subject><ispartof>Journal of medicinal chemistry, 1992-08, Vol.35 (16), p.3080-3081</ispartof><rights>1993 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a298t-6a8da908a4cdcf23c437efd6207d328bd182397957b03089335da055ebba57bc3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/jm00094a024$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/jm00094a024$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>315,782,786,2767,27083,27931,27932,56745,56795</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4381262$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1501235$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Humber, David C</creatorcontrib><creatorcontrib>Cammack, Nicholas</creatorcontrib><creatorcontrib>Coates, Jonathan A. V</creatorcontrib><creatorcontrib>Cobley, Kevin N</creatorcontrib><creatorcontrib>Orr, David C</creatorcontrib><creatorcontrib>Storer, Richard</creatorcontrib><creatorcontrib>Weingarten, Gordon G</creatorcontrib><creatorcontrib>Weir, Malcolm P</creatorcontrib><title>Penicillin derived C2-symmetric dimers as novel inhibitors of HIV-1 proteinase</title><title>Journal of medicinal chemistry</title><addtitle>J. Med. Chem</addtitle><subject>AIDS/HIV</subject><subject>Antiviral Agents - pharmacology</subject><subject>Cell Line</subject><subject>Chemistry</subject><subject>Cytopathogenic Effect, Viral - drug effects</subject><subject>Dioxoles - pharmacology</subject><subject>Dioxoles - therapeutic use</subject><subject>Exact sciences and technology</subject><subject>Heterocyclic compounds</subject><subject>Heterocyclic compounds with n hetero atom and also o and/or s, se, te hetero atoms</subject><subject>HIV Protease Inhibitors</subject><subject>HIV-1 - drug effects</subject><subject>HIV-1 - enzymology</subject><subject>HIV-1 - physiology</subject><subject>Humans</subject><subject>Organic chemistry</subject><subject>Penicillins - pharmacology</subject><subject>Preparations and properties</subject><subject>Virus Replication - drug effects</subject><subject>X-Ray Diffraction</subject><issn>0022-2623</issn><issn>1520-4804</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkE1PGzEQhi1UlIa0J86V9lCVA1oY27vZ3WMVAYmKQqSmXK1Ze1Z1uh_B3iDy73G0EfTAaax5H82MH8bOOVxxEPx60wBAkSCI5ISNeSogTnJIPrExgBCxmAr5mZ15vwmY5EKO2IinEB7pmC1X1Fpt69q2kSFnn8lEMxH7fdNQ76yOjG3I-Qh91HbPVEe2_WtL23eh11XRfPEY82jrup5si56-sNMKa09fj3XC_tzerGfz-P7hbjH7eR-jKPI-nmJusIAcE210JaROZEaVmQrIjBR5aXguZJEVaVaChLyQMjUIaUpliaGn5YT9GOaG1U878r1qrNdU19hSt_MqO_xT8CKAlwOoXee9o0ptnW3Q7RUHdbCn_rMX6G_HsbuyIfPODrpC_v2Yo9dYVw5bbf0blsicH2xPWDxg1vf08haj-6emmcxStV79Vr-SRznPipVaBv5i4FF7tel2rg3uPjzwFYvAkRE</recordid><startdate>19920801</startdate><enddate>19920801</enddate><creator>Humber, David C</creator><creator>Cammack, Nicholas</creator><creator>Coates, Jonathan A. V</creator><creator>Cobley, Kevin N</creator><creator>Orr, David C</creator><creator>Storer, Richard</creator><creator>Weingarten, Gordon G</creator><creator>Weir, Malcolm P</creator><general>American Chemical Society</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19920801</creationdate><title>Penicillin derived C2-symmetric dimers as novel inhibitors of HIV-1 proteinase</title><author>Humber, David C ; Cammack, Nicholas ; Coates, Jonathan A. V ; Cobley, Kevin N ; Orr, David C ; Storer, Richard ; Weingarten, Gordon G ; Weir, Malcolm P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a298t-6a8da908a4cdcf23c437efd6207d328bd182397957b03089335da055ebba57bc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>AIDS/HIV</topic><topic>Antiviral Agents - pharmacology</topic><topic>Cell Line</topic><topic>Chemistry</topic><topic>Cytopathogenic Effect, Viral - drug effects</topic><topic>Dioxoles - pharmacology</topic><topic>Dioxoles - therapeutic use</topic><topic>Exact sciences and technology</topic><topic>Heterocyclic compounds</topic><topic>Heterocyclic compounds with n hetero atom and also o and/or s, se, te hetero atoms</topic><topic>HIV Protease Inhibitors</topic><topic>HIV-1 - drug effects</topic><topic>HIV-1 - enzymology</topic><topic>HIV-1 - physiology</topic><topic>Humans</topic><topic>Organic chemistry</topic><topic>Penicillins - pharmacology</topic><topic>Preparations and properties</topic><topic>Virus Replication - drug effects</topic><topic>X-Ray Diffraction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Humber, David C</creatorcontrib><creatorcontrib>Cammack, Nicholas</creatorcontrib><creatorcontrib>Coates, Jonathan A. V</creatorcontrib><creatorcontrib>Cobley, Kevin N</creatorcontrib><creatorcontrib>Orr, David C</creatorcontrib><creatorcontrib>Storer, Richard</creatorcontrib><creatorcontrib>Weingarten, Gordon G</creatorcontrib><creatorcontrib>Weir, Malcolm P</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of medicinal chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Humber, David C</au><au>Cammack, Nicholas</au><au>Coates, Jonathan A. V</au><au>Cobley, Kevin N</au><au>Orr, David C</au><au>Storer, Richard</au><au>Weingarten, Gordon G</au><au>Weir, Malcolm P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Penicillin derived C2-symmetric dimers as novel inhibitors of HIV-1 proteinase</atitle><jtitle>Journal of medicinal chemistry</jtitle><addtitle>J. Med. Chem</addtitle><date>1992-08-01</date><risdate>1992</risdate><volume>35</volume><issue>16</issue><spage>3080</spage><epage>3081</epage><pages>3080-3081</pages><issn>0022-2623</issn><eissn>1520-4804</eissn><coden>JMCMAR</coden><cop>Washington, DC</cop><pub>American Chemical Society</pub><pmid>1501235</pmid><doi>10.1021/jm00094a024</doi><tpages>2</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-2623 |
| ispartof | Journal of medicinal chemistry, 1992-08, Vol.35 (16), p.3080-3081 |
| issn | 0022-2623 1520-4804 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_73123219 |
| source | MEDLINE; ACS Publications |
| subjects | AIDS/HIV Antiviral Agents - pharmacology Cell Line Chemistry Cytopathogenic Effect, Viral - drug effects Dioxoles - pharmacology Dioxoles - therapeutic use Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with n hetero atom and also o and/or s, se, te hetero atoms HIV Protease Inhibitors HIV-1 - drug effects HIV-1 - enzymology HIV-1 - physiology Humans Organic chemistry Penicillins - pharmacology Preparations and properties Virus Replication - drug effects X-Ray Diffraction |
| title | Penicillin derived C2-symmetric dimers as novel inhibitors of HIV-1 proteinase |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-04T20%3A35%3A16IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Penicillin%20derived%20C2-symmetric%20dimers%20as%20novel%20inhibitors%20of%20HIV-1%20proteinase&rft.jtitle=Journal%20of%20medicinal%20chemistry&rft.au=Humber,%20David%20C&rft.date=1992-08-01&rft.volume=35&rft.issue=16&rft.spage=3080&rft.epage=3081&rft.pages=3080-3081&rft.issn=0022-2623&rft.eissn=1520-4804&rft.coden=JMCMAR&rft_id=info:doi/10.1021/jm00094a024&rft_dat=%3Cproquest_cross%3E73123219%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=73123219&rft_id=info:pmid/1501235&rfr_iscdi=true |