Vasorelaxant effects of eugenol on rat thoracic aorta

Eugenol is a natural pungent substance and the main component of clove oil, with vasorelaxant action. To elucidate some of the possible mechanisms involved in this action isometric tension was measured in aortic rings from male Wistar rats precontracted with phenylephrine (PHE, 10 −7 M) or KCl (75 m...

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Veröffentlicht in:	Vascular pharmacology 2003, Vol.40 (1), p.59-66
Hauptverfasser:	Damiani, Carlos Estevam Nolf, Rossoni, Luciana Venturini, Vassallo, Dalton Valentim
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta, Thoracic - drug effects Aorta, Thoracic - physiology Biological and medical sciences Cardiovascular system Dose-Response Relationship, Drug Endothelium Eugenol Eugenol - pharmacology General pharmacology In Vitro Techniques l-NAME Male Medical sciences Nitric oxide Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phenylephrine Rats Rats, Wistar Vascular reactivity Vasoconstriction - drug effects Vasoconstriction - physiology Vasodilation - drug effects Vasodilation - physiology Vasodilator Agents - pharmacology Vasodilator agents. Cerebral vasodilators
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