Naltrindole retards tolerance development to morphine-induced effects on EEG and EEG power spectra

In the present study, EEG and EEG power spectra were used to assess the effects of naltrindole, a selective δ opioid antagonist, on the development of tolerance to morphine. Adult female Sprague-Dawley rats were implanted with cortical EEG electrodes and permanent indwelling i.c.v. and i.v. cannulas...

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