alpha1- and alpha2-adrenergic vasoconstriction is blunted in contracting human muscle

Sympathetic vasoconstriction is blunted in the vascular beds of contracting skeletal muscles. We sought to determine whether this blunted vasoconstriction is specific for post-junctional alpha1- or alpha2-adrenergic receptors. We measured forearm blood flow (Doppler ultrasound) and calculated the va...

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Veröffentlicht in:	The Journal of physiology 2003-03, Vol.547 (Pt 3), p.971-976
Hauptverfasser:	Rosenmeier, Jaya B, Dinenno, Frank A, Fritzlar, Sandy J, Joyner, Michael J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic alpha-Agonists - administration & dosage Adrenergic Uptake Inhibitors - administration & dosage Adult Clonidine - administration & dosage Forearm - blood supply Humans Male Muscle Contraction - physiology Muscle, Skeletal - blood supply Muscle, Skeletal - physiology Phenylephrine - administration & dosage Receptors, Adrenergic, alpha-1 - metabolism Receptors, Adrenergic, alpha-2 - metabolism Tyramine - administration & dosage Vasoconstriction - drug effects Vasoconstriction - physiology
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