Interindividual variations in constitutive interleukin-10 messenger RNA and protein levels and their association with genetic polymorphisms

Genetic variations in the interleukin (IL)-10 gene promoter have been associated with levels of induced production of IL-10, disease susceptibility, and allograft rejection. Small amounts of this cytokine are constitutively produced and are important in maintaining the physiologic function of the cy...

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Veröffentlicht in:	Transplantation 2003-03, Vol.75 (5), p.711-717
Hauptverfasser:	SUAREZ, Ana, CASTRO, Patricia, ALONSO, Rebeca, MOZO, Lourdes, GUTIERRE, Carmen
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Biological and medical sciences Fundamental and applied biological sciences. Psychology Gene Frequency Genotype Haplotypes Humans Inflammation Interleukin-10 - genetics Interleukin-10 - metabolism Lipopolysaccharides - pharmacology Molecular and cellular biology Osmolar Concentration Polymorphism, Genetic - physiology Promoter Regions, Genetic - physiology RNA, Messenger - metabolism
Online-Zugang:	Volltext
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