Mutations in the human muscle LIM protein gene in families with hypertrophic cardiomyopathy

Muscle LIM protein (MLP) is an essential nuclear regulator of myogenic differentiation. Additionally, it may act as an integrator of protein assembly of the actin-based cytoskeleton. MLP-knockout mice develop a marked cardiac hypertrophy reaction and dilated cardiomyopathy (DCM). MLP is therefore a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2003-03, Vol.107 (10), p.1390-1395
Hauptverfasser:	GEIER, Christian, PERROT, Andreas, FÜRST, Dieter O, VORNWALD, Arnold, VON HODENBERG, Eberhard, NÜRNBERG, Peter, SCHEFFOLD, Thomas, DIETZ, Rainer, OSTERZIEL, Karl Josef, ÖZCELIK, Cemil, BINNER, Priska, COUNSELL, Damian, HOFFMANN, Katrin, PILZ, Bernhard, MARTINIAK, Yvonne, GEHMLICH, Katja, VAN DER VEN, Peter F. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Actinin - metabolism Adolescent Adult Aged Amino Acid Sequence Biological and medical sciences Cardiology. Vascular system Cardiomyopathy, Hypertrophic - diagnosis Cardiomyopathy, Hypertrophic - genetics Family Health Female Genetic Predisposition to Disease Heart Humans LIM Domain Proteins Male Medical sciences Middle Aged Models, Molecular Molecular Sequence Data Muscle Proteins - chemistry Muscle Proteins - genetics Muscle Proteins - metabolism Mutation, Missense Myocarditis. Cardiomyopathies Pedigree Protein Structure, Tertiary Sequence Alignment
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!