In vivo anti-nociceptive and anti-inflammatory effect of the two triterpenes, ursolic acid and 23-hydroxyursolic acid, from Cussonia bancoensis

Triterpenoids, ursolic acid (1) and 23-hydroxyursolic acid (2) were obtained from the hydrolysis of BuOH fraction of Cussonia bancoensis extract to test antinociceptive and anti-inflammatory effect of C. bancoensis (Araliaceae). Compound 1 and 2 exhibited anti-nociceptive effects, which were determi...

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Veröffentlicht in:	Archives of pharmacal research 2003-02, Vol.26 (2), p.143-146
Hauptverfasser:	Tapondjou, L A, Lontsi, David, Sondengam, Beibam Luc, Choi, Jongwon, Lee, Kyung-Tae, Jung, Hyun-Ju, Park, Hee-Juhn
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics - chemistry Analgesics - isolation & purification Analgesics - therapeutic use Animals Anti-Inflammatory Agents, Non-Steroidal - chemistry Anti-Inflammatory Agents, Non-Steroidal - isolation & purification Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Araliaceae - chemistry Disease Models, Animal Edema - drug therapy Korea Male Medicine, East Asian Traditional Mice Mice, Inbred ICR Molecular Structure Pain - drug therapy Plant Bark - chemistry Plant Extracts Plant Leaves - chemistry Rats Rats, Sprague-Dawley Triterpenes - chemistry Triterpenes - isolation & purification Triterpenes - therapeutic use Ursolic Acid
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