Translational Control of Protein Synthesis in Muscle and Liver of Growth Hormone-Treated Pigs

GH treatment increases protein deposition and the efficiency of dietary protein used for growth. To identify the mechanisms that regulate tissue protein synthesis in response to exogenous GH treatment, fully fed, growing swine were treated with GH for 7 d. Fasted and fed pigs were infused with [1-13...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2003-04, Vol.144 (4), p.1273-1283
Hauptverfasser:	Bush, Jill A, Kimball, Scot R, O’Connor, Pamela M. J, Suryawan, Agus, Orellana, Renan A, Nguyen, Hanh V, Jefferson, Leonard S, Davis, Teresa A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood Glucose Body Weight - drug effects Carrier Proteins - metabolism Eating Efficiency Eukaryotic Initiation Factor-2 - metabolism Eukaryotic Initiation Factor-2B - metabolism Eukaryotic Initiation Factor-4E - metabolism Eukaryotic Initiation Factor-4G - metabolism Fasting Female Fundamental and applied biological sciences. Psychology Glucagon - blood Growth Hormone - pharmacology Growth hormones Initiation factor eIF-4E Initiation factor eIF-4G Insulin - blood Insulin-Like Growth Factor I - metabolism Kinases Leucine Liver Liver - physiology mRNA Muscle, Skeletal - physiology Muscles Phosphoproteins - metabolism Phosphorylation Protein biosynthesis Protein Biosynthesis - drug effects Protein Biosynthesis - physiology Protein synthesis Protein-Serine-Threonine Kinases Proteins Proto-Oncogene Proteins - metabolism Proto-Oncogene Proteins c-akt Ribonucleic acid Ribosomal Protein S6 Kinases - metabolism RNA Skeletal muscle Sus scrofa Swine Transcription tRNA
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