SNR1 is an essential subunit in a subset of drosophila brm complexes, targeting specific functions during development

The snr1 gene of Drosophila melanogaster encodes a conserved component of the multiprotein Brahma (Brm) complex, a counterpart to the SWI/SNF complexes that participate in ATP-dependent chromatin remodeling. Loss-of-function and null mutations in the snr1 gene reveal its essential role in Drosophila...

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Veröffentlicht in:	Developmental biology 2003-01, Vol.253 (2), p.291-308
Hauptverfasser:	Zraly, Claudia B, Marenda, Daniel R, Nanchal, Runjhun, Cavalli, Giacomo, Muchardt, Christian, Dingwall, Andrew K
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Amino Acid Sequence Animals Animals, Genetically Modified Brahma BRM Cell Cycle Proteins - chemistry Cell Cycle Proteins - genetics Cell Cycle Proteins - physiology Chromatin Drosophila Drosophila melanogaster - genetics Drosophila melanogaster - growth & development Drosophila melanogaster - physiology Drosophila Proteins - chemistry Drosophila Proteins - genetics Drosophila Proteins - physiology Female Gene Expression Regulation, Developmental Genes, Insect INI1 Male Molecular Sequence Data Mosaicism Mutation Phenotype PolII Polytene Protein Subunits SNF5 SNR1 SWI/SNF Trans-Activators - chemistry Trans-Activators - genetics Trans-Activators - physiology Transcription Factors - chemistry Transcription Factors - genetics Transcription Factors - physiology Transcriptional Activation
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