Levels of mRNA Coding for Motoneuron Growth-Promoting Factors are Increased in Denervated Muscle

Partial denervation of skeletal muscle induces sprouting of axons remaining within the muscle, possibly as a result of increased synthesis by denervated muscle fibers of motoneuron growth-promoting factors. Direct verification of this hypothesis has not been possible because the molecules responsibl...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1992-08, Vol.89 (15), p.7194-7198
Hauptverfasser:	Rassendren, François A., Bloch-Gallego, Evelyne, Tanaka, Hideaki, Henderson, Christopher E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Animals Antibodies Biological and medical sciences Cell Survival Cells, Cultured Chick Embryo Chickens Denervation Fundamental and applied biological sciences. Psychology Growth Substances - genetics Innervation Medical research Membrane Proteins - genetics Messenger RNA Motor Neurons - cytology Motor Neurons - physiology Muscle Denervation Muscles Muscles - innervation Muscles - physiology Muscular system Nervous system Neurites Neurites - physiology Neurons Oocytes Oocytes - physiology Poly A - genetics Poly A - isolation & purification Protein hormones. Growth factors. Cytokines Proteins Receptors, Nicotinic - genetics Ribonucleic acid RNA RNA - genetics RNA - isolation & purification RNA, Messenger - genetics RNA, Messenger - metabolism Sodium Channels - physiology Space life sciences Spinal cord Spinal Cord - physiology Sprouting Xenopus
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