Rapid cycling bipolar disorder after left temporal polar damage
The case of a 48-year-old woman with rapid cycling bipolar disorder subsequent to a traumatic brain injury is reported. Both depressive and manic episodes had an average duration of ~1 month, alternating without stable euthymic periods. Neuroradiological examinations revealed a circumscribed lesion...
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Veröffentlicht in: | Brain injury 2003-04, Vol.17 (4), p.355-358 |
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description | The case of a 48-year-old woman with rapid cycling bipolar disorder subsequent to a traumatic brain injury is reported. Both depressive and manic episodes had an average duration of ~1 month, alternating without stable euthymic periods. Neuroradiological examinations revealed a circumscribed lesion in the left temporal pole. After 1 year without treatment, psychiatric intervention and pharmacotherapy was initiated. Her mood swings were successfully treated with the co-administration of valproate and lithium. Case reports of rapid cycling bipolar disorder after traumatic brain injury are very rare and this case supports the idea that temporal polar dysfunction is a candidate for the neurobiological basis of rapid cycling bipolar disorder. |
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Both depressive and manic episodes had an average duration of ~1 month, alternating without stable euthymic periods. Neuroradiological examinations revealed a circumscribed lesion in the left temporal pole. After 1 year without treatment, psychiatric intervention and pharmacotherapy was initiated. Her mood swings were successfully treated with the co-administration of valproate and lithium. Case reports of rapid cycling bipolar disorder after traumatic brain injury are very rare and this case supports the idea that temporal polar dysfunction is a candidate for the neurobiological basis of rapid cycling bipolar disorder.</description><identifier>ISSN: 0269-9052</identifier><identifier>EISSN: 1362-301X</identifier><identifier>DOI: 10.1080/0269905031000070170</identifier><identifier>PMID: 12637187</identifier><identifier>CODEN: BRAIEO</identifier><language>eng</language><publisher>London: Informa UK Ltd</publisher><subject>Accidents, Traffic ; Biological and medical sciences ; Bipolar Disorder - etiology ; Brain Injuries - diagnosis ; Brain Injuries - psychology ; Female ; Humans ; Injuries of the nervous system and the skull. Diseases due to physical agents ; Magnetic Resonance Imaging ; Medical sciences ; Middle Aged ; Neuropsychological Tests ; Temporal Lobe - injuries ; Traumas. 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Both depressive and manic episodes had an average duration of ~1 month, alternating without stable euthymic periods. Neuroradiological examinations revealed a circumscribed lesion in the left temporal pole. After 1 year without treatment, psychiatric intervention and pharmacotherapy was initiated. Her mood swings were successfully treated with the co-administration of valproate and lithium. Case reports of rapid cycling bipolar disorder after traumatic brain injury are very rare and this case supports the idea that temporal polar dysfunction is a candidate for the neurobiological basis of rapid cycling bipolar disorder.</description><subject>Accidents, Traffic</subject><subject>Biological and medical sciences</subject><subject>Bipolar Disorder - etiology</subject><subject>Brain Injuries - diagnosis</subject><subject>Brain Injuries - psychology</subject><subject>Female</subject><subject>Humans</subject><subject>Injuries of the nervous system and the skull. Diseases due to physical agents</subject><subject>Magnetic Resonance Imaging</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neuropsychological Tests</subject><subject>Temporal Lobe - injuries</subject><subject>Traumas. 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Diseases due to physical agents</topic><topic>Magnetic Resonance Imaging</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neuropsychological Tests</topic><topic>Temporal Lobe - injuries</topic><topic>Traumas. Diseases due to physical agents</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Murai, Toshiya</creatorcontrib><creatorcontrib>Fujimoto, Shinsuke</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Brain injury</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Murai, Toshiya</au><au>Fujimoto, Shinsuke</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Rapid cycling bipolar disorder after left temporal polar damage</atitle><jtitle>Brain injury</jtitle><addtitle>Brain Inj</addtitle><date>2003-04-01</date><risdate>2003</risdate><volume>17</volume><issue>4</issue><spage>355</spage><epage>358</epage><pages>355-358</pages><issn>0269-9052</issn><eissn>1362-301X</eissn><coden>BRAIEO</coden><abstract>The case of a 48-year-old woman with rapid cycling bipolar disorder subsequent to a traumatic brain injury is reported. Both depressive and manic episodes had an average duration of ~1 month, alternating without stable euthymic periods. Neuroradiological examinations revealed a circumscribed lesion in the left temporal pole. After 1 year without treatment, psychiatric intervention and pharmacotherapy was initiated. Her mood swings were successfully treated with the co-administration of valproate and lithium. Case reports of rapid cycling bipolar disorder after traumatic brain injury are very rare and this case supports the idea that temporal polar dysfunction is a candidate for the neurobiological basis of rapid cycling bipolar disorder.</abstract><cop>London</cop><pub>Informa UK Ltd</pub><pmid>12637187</pmid><doi>10.1080/0269905031000070170</doi><tpages>4</tpages></addata></record> |
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subjects | Accidents, Traffic Biological and medical sciences Bipolar Disorder - etiology Brain Injuries - diagnosis Brain Injuries - psychology Female Humans Injuries of the nervous system and the skull. Diseases due to physical agents Magnetic Resonance Imaging Medical sciences Middle Aged Neuropsychological Tests Temporal Lobe - injuries Traumas. Diseases due to physical agents |
title | Rapid cycling bipolar disorder after left temporal polar damage |
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