Rapid cycling bipolar disorder after left temporal polar damage

The case of a 48-year-old woman with rapid cycling bipolar disorder subsequent to a traumatic brain injury is reported. Both depressive and manic episodes had an average duration of ~1 month, alternating without stable euthymic periods. Neuroradiological examinations revealed a circumscribed lesion...

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Veröffentlicht in:Brain injury 2003-04, Vol.17 (4), p.355-358
Hauptverfasser: Murai, Toshiya, Fujimoto, Shinsuke
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Fujimoto, Shinsuke
description The case of a 48-year-old woman with rapid cycling bipolar disorder subsequent to a traumatic brain injury is reported. Both depressive and manic episodes had an average duration of ~1 month, alternating without stable euthymic periods. Neuroradiological examinations revealed a circumscribed lesion in the left temporal pole. After 1 year without treatment, psychiatric intervention and pharmacotherapy was initiated. Her mood swings were successfully treated with the co-administration of valproate and lithium. Case reports of rapid cycling bipolar disorder after traumatic brain injury are very rare and this case supports the idea that temporal polar dysfunction is a candidate for the neurobiological basis of rapid cycling bipolar disorder.
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Both depressive and manic episodes had an average duration of ~1 month, alternating without stable euthymic periods. Neuroradiological examinations revealed a circumscribed lesion in the left temporal pole. After 1 year without treatment, psychiatric intervention and pharmacotherapy was initiated. Her mood swings were successfully treated with the co-administration of valproate and lithium. 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Both depressive and manic episodes had an average duration of ~1 month, alternating without stable euthymic periods. Neuroradiological examinations revealed a circumscribed lesion in the left temporal pole. After 1 year without treatment, psychiatric intervention and pharmacotherapy was initiated. Her mood swings were successfully treated with the co-administration of valproate and lithium. Case reports of rapid cycling bipolar disorder after traumatic brain injury are very rare and this case supports the idea that temporal polar dysfunction is a candidate for the neurobiological basis of rapid cycling bipolar disorder.</description><subject>Accidents, Traffic</subject><subject>Biological and medical sciences</subject><subject>Bipolar Disorder - etiology</subject><subject>Brain Injuries - diagnosis</subject><subject>Brain Injuries - psychology</subject><subject>Female</subject><subject>Humans</subject><subject>Injuries of the nervous system and the skull. 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source MEDLINE; Taylor & Francis Medical Library - CRKN; Taylor & Francis Journals Complete
subjects Accidents, Traffic
Biological and medical sciences
Bipolar Disorder - etiology
Brain Injuries - diagnosis
Brain Injuries - psychology
Female
Humans
Injuries of the nervous system and the skull. Diseases due to physical agents
Magnetic Resonance Imaging
Medical sciences
Middle Aged
Neuropsychological Tests
Temporal Lobe - injuries
Traumas. Diseases due to physical agents
title Rapid cycling bipolar disorder after left temporal polar damage
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