Ruthenium(III) Polyaminocarboxylate Complexes: Efficient and Effective Nitric Oxide Scavengers

The preparation of two RuIII polyaminocarboxylate complexes, AMD6245 and AMD6221, and their nitrosyl analogues, AMD6204, AMD6263, and AMD3689, is described. The compounds are characterized by IR, ES-MS, and 13C and 15N NMR spectroscopy where appropriate and cyclic voltammetry. The crystal structures...

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Veröffentlicht in:	Inorganic chemistry 2003-03, Vol.42 (6), p.1868-1876
Hauptverfasser:	Cameron, Beth R, Darkes, Marilyn C, Yee, Helen, Olsen, Micki, Fricker, Simon P, Skerlj, Renato T, Bridger, Gary J, Davies, Nathan A, Wilson, Michael T, Rose, David J, Zubieta, Jon
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Crystallography, X-Ray Dose-Response Relationship, Drug Electrochemistry Electron Spin Resonance Spectroscopy Kinetics Macrophages - drug effects Mice Molecular Structure Nitric Oxide - metabolism Organometallic Compounds - chemical synthesis Organometallic Compounds - chemistry Organometallic Compounds - pharmacology Pentetic Acid - analogs & derivatives Pentetic Acid - chemical synthesis Pentetic Acid - chemistry Pentetic Acid - pharmacology Ruthenium - chemistry
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