Anti-inflammatory cytokine response and the development of multiple organ failure in severe sepsis

Background: The production of proinflammatory cytokines activates the systemic inflammatory response in sepsis. Patients also develop a compensatory anti‐inflammatory reaction, which may have an important down‐regulatory effect on the overactive inflammation. However, the role of this anti‐inflamma...

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Veröffentlicht in:	Acta anaesthesiologica Scandinavica 2003-03, Vol.47 (3), p.319-325
Hauptverfasser:	Loisa, P., Rinne, T., Laine, S., Hurme, M., Kaukinen, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood Pressure - drug effects Cardiac Output - drug effects Cytokines - biosynthesis Emergency and intensive care: infection, septic shock Female Humans Intensive care medicine Interleukin-1 - biosynthesis interleukin-10 Interleukin-10 - biosynthesis interleukin-6 Interleukin-6 - biosynthesis Male Medical sciences Middle Aged multiple organ failure Multiple Organ Failure - metabolism Multiple Organ Failure - microbiology Multiple Organ Failure - physiopathology Oxygen - blood Prospective Studies sepsis Sepsis - metabolism Sepsis - microbiology Sepsis - physiopathology Vascular Resistance - drug effects
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