A temperature-sensitive step in exocytosis

We have examined the temperature sensitivity of exocytosis in digitonin-permeabilized chromaffin cells. The time course of secretion is markedly slowed by incubating the cells at 18 degrees C rather than 27 degrees C. We have previously shown that secretion has both ATP-dependent and ATP-independent...

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Veröffentlicht in:	The Journal of biological chemistry 1992-08, Vol.267 (23), p.16226-16229
Hauptverfasser:	BITTNER, M. A, HOLZ, R. W
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Adenosine Triphosphate - pharmacology Adrenal Medulla - metabolism Animals Biological and medical sciences Cattle Cell physiology Cells, Cultured chromaffin cells Digitonin - pharmacology Exocytosis Fundamental and applied biological sciences. Psychology Kinetics Molecular and cellular biology Norepinephrine - metabolism Secretion. Exocytosis sensitivity Temperature Time Factors
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