Crystallographic binding studies with triosephosphate isomerases: Conformational changes induced by substrate and substrate-analogues

TIM catalyses the interconversion of a triosephosphate aldehyde into a triosephosphate ketone. This is a simple chemical reaction in which only protons are transferred, The crystallographic studies of TIM from chicken, yeast and trypanosome complexed with substrate and substrate analogues are discus...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	FEBS Letters 1992-07, Vol.307 (1), p.34-39
Hauptverfasser:	Wierenga, R.K., Borcher, T.V., Noble, M.E.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	2-phosphoglycollate 2PG Analytical, structural and metabolic biochemistry Biological and medical sciences Catalysis chickens conformation Conformational change Crystallographic binding study d-glyceraldehyde-3-phosphate DHAP dihydroxyacetone phosphate Dimer Enzymes and enzyme inhibitors Fundamental and applied biological sciences. Psychology G3P GAP glycerol-3-phosphate interaction Isomerases Ligands PGH phosphoglycolohydroxamate Protein Conformation reviews RMS root mean square Saccharomyces cerevisiae Substrate Specificity substrates TIM triose-phosphate isomerase Triose-Phosphate Isomerase - chemistry Triose-Phosphate Isomerase - metabolism Triosephosphate isomerase triosephosphate isomerase (E.C, 5.3.1.1.) X-ray crystallography X-Ray Diffraction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!