Inhibition of Growth Hormone Excess Reduces Insulin Resistance and Ovarian Dysfunction in a Lean Case of Polycystic Ovary Syndrome with a Growth-Hormone-Producing Pituitary Adenoma

A 23-year-old female with polycystic ovary syndrome (PCOS) and a growth-hormone (GH)-producing pituitary adenoma is described. A reduction in the elevated GH levels to normal levels following the administration of dopaminergic agents decreased plasma insulin-like growth factor (IGF)-1 and ovarian dy...

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Veröffentlicht in:	Hormone research 2003-01, Vol.59 (3), p.149-155
Hauptverfasser:	Hashimoto, Shigeatsu, Yatabe, Jun-ichi, Midorikawa, Sanae, Sanada, Hironobu, Watanabe, Tsuyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Acanthosis Nigricans - complications Acromegaly - complications Adenoma - metabolism Adult Bromocriptine - therapeutic use Case Report Dopamine Agents - therapeutic use Female Glucose Tolerance Test Human Growth Hormone - antagonists & inhibitors Human Growth Hormone - biosynthesis Humans Insulin - physiology Insulin resistance Insulin Resistance - physiology Insulin-Like Growth Factor I - physiology Lisuride - analogs & derivatives Lisuride - therapeutic use Magnetic Resonance Imaging Menstrual Cycle - drug effects Ovary - pathology Ovary - physiopathology Pancreatic Function Tests Pituitary Function Tests Pituitary Neoplasms - metabolism Polycystic Ovary Syndrome - drug therapy Polycystic Ovary Syndrome - pathology Polycystic Ovary Syndrome - physiopathology Theca Cells - physiology
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