A hypothalamic activator of calmodulin-dependent enzymes is thymosin beta 4 (1-39)

A new class of stimulators of basal activity of a number of calmodulin-dependent enzymes have been previously isolated from bovine hypothalamus. One of these stimulators, denoted as C3, has been purified to homogeneity by reverse phase HPLC and tentatively identified as thymosin beta 4 (1-39) by mas...

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Veröffentlicht in:	Neurochemical research 1992-08, Vol.17 (8), p.773-777
Hauptverfasser:	Galoyan, A A, Gurvitis BYa, Shuvalova, L A, Davis, M T, Shively, J E, Lee, T D
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino Acids - analysis Animals Calmodulin - pharmacology Cattle Chromatography, High Pressure Liquid Enzyme Activation - drug effects Hypothalamus - chemistry Mass Spectrometry Molecular Sequence Data Muscles - enzymology Myosin-Light-Chain Kinase - metabolism Peptide Fragments - chemistry Peptide Fragments - pharmacology Rabbits Thymosin - analogs & derivatives Thymosin - chemistry Thymosin - isolation & purification Thymosin - pharmacology
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